As of November 6, 2026, 5 holders' latest Schedule 13D or 13G filings report owning 5% or more of LeonaBio, Inc. The largest reported stake is Sermonix Pharmaceuticals, Inc.'s, at 25.1%. 17 filings are on record since October 10, 2025 (Schedule 13D/A, October 28, 2026).
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Key facts
- · Reporting person: Great Point Partners, LLC · Sole voting: 0 · Shared voting: 474,345 · Sole dispositive: 0 · Shared dispositive: 474,345 · SCHEDULE 13G, 2026-11-04
- · Reporting person: Sermonix Pharmaceuticals, Inc. · Sole voting: 0 · Shared voting: 3,149,470 · Sole dispositive: 0 · Shared dispositive: 3,149,470 · SCHEDULE 13D/A, 2026-10-28
- · Holder: Perceptive Advisors LLC · Percent: 19.99% · Shares: 1,889,403 · SCHEDULE 13D/A
- · Holder: Sermonix Pharmaceuticals, Inc. · Percent: 36.9% · SCHEDULE 13D
- · Holder: Perceptive Advisors LLC · Percent: 19.99% · SCHEDULE 13D/A
LeonaBio, Inc. has 17 Schedule 13D or 13G filings on record since 2025-10-10. 5 holders' latest filing reports 5% or more of common stock, $0.0001 par value per share. Each figure below is the holder's own, as filed, with the filing linked.
Holders
| Holder | Percent | Shares | Latest | Event date |
|---|---|---|---|---|
| Sermonix Pharmaceuticals, Inc. | 25.1% | 3,149,470 | SCHEDULE 13D/A, 2026-10-28 | 2026-10-26 |
| Perceptive Advisors LLC | 19.99% | 1,889,403 | SCHEDULE 13D/A, 2026-10-26 | 2026-10-26 |
| 12.1% | 1,492,521 | SCHEDULE 13G/A, 2026-08-20 | 2026-08-18 | |
| ADAR1 Capital Management, LLC | 7.7% | 727,481 | SCHEDULE 13G, 2026-05-15 | 2026-03-31 |
| Great Point Partners, LLC | 5.03% | 474,345 | SCHEDULE 13G, 2026-11-04 | 2026-10-28 |
| 4.09% | 161,218 | SCHEDULE 13G/A, 2025-10-10 | 2025-10-01 | |
| Baselake Partners, LP | 1.9% | 75,789 | SCHEDULE 13G/A, 2026-02-06 | 2025-12-31 |
| BML Investment Partners, L.P. | 0% | 0 | SCHEDULE 13G/A, 2025-12-18 | 2025-12-18 |
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Keep reading
More on LeonaBio, Inc. and the records around it.
LeonaBio, Inc. elsewhere on the record
Companies that share a holder
- Oliveira Steven Michael also filed stake reports on 1 other company: Forte Biosciences, Inc. (Jan 2026)
- ACORN BIOVENTURES, L.P. also filed stake reports on 5 other companies: Karyopharm Therapeutics Inc. (Oct 2026), enGene Therapeutics Inc. (Jul 2026), OnKure Therapeutics, Inc. (Apr 2026)
- Baselake Partners, LP also filed stake reports on 7 other companies: KIORA PHARMACEUTICALS, INC. (Sep 2026), Passage Bio, Inc. (Jun 2026), Generation Bio Co. (Feb 2026)
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What the Full Report on LeonaBio, Inc. covers
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Voting and dispositive power, as filed
| Reporting person | Sole voting | Shared voting | Sole dispositive | Shared dispositive | Filing |
|---|---|---|---|---|---|
| Sermonix Pharmaceuticals, Inc. | 0 | 3,149,470 | 0 | 3,149,470 | SCHEDULE 13D/A, 2026-10-28 |
| Portman David J. | 0 | 3,149,470 | 0 | 3,149,470 | SCHEDULE 13D/A, 2026-10-28 |
| Perceptive Advisors LLC | 0 | 1,889,403 | 0 | 1,889,403 | SCHEDULE 13D/A, 2026-10-26 |
| Joseph Edelman | 0 | 1,889,403 | 0 | 1,889,403 | SCHEDULE 13D/A, 2026-10-26 |
| Perceptive Life Sciences Master Fund, Ltd. | 0 | 1,559,647 | 0 | 1,559,647 | SCHEDULE 13D/A, 2026-10-26 |
| Perceptive Xontogeny Venture Fund II, LP | 0 | 359,837 | 0 | 359,837 | SCHEDULE 13D/A, 2026-10-26 |
| Acorn Bioventures, L.P. | 0 | 480,653 | 0 | 480,653 | SCHEDULE 13G/A, 2026-08-20 |
| Acorn Capital Advisors Gp, LLC | 0 | 480,653 | 0 | 480,653 | SCHEDULE 13G/A, 2026-08-20 |
| Acorn Bioventures 2, L.P. | 0 | 663,763 | 0 | 663,763 | SCHEDULE 13G/A, 2026-08-20 |
| Acorn Capital Advisors GP 2, LLC | 0 | 663,763 | 0 | 663,763 | SCHEDULE 13G/A, 2026-08-20 |
| Anders Hove | 0 | 1,492,521 | 0 | 1,492,521 | SCHEDULE 13G/A, 2026-08-20 |
| Great Point Partners, LLC | 0 | 474,345 | 0 | 474,345 | SCHEDULE 13G, 2026-11-04 |
| Dr. Jeffrey R. Jay, M.D. | 0 | 474,345 | 0 | 474,345 | SCHEDULE 13G, 2026-11-04 |
| Ms. Lillian Nordahl | 0 | 474,345 | 0 | 474,345 | SCHEDULE 13G, 2026-11-04 |
The latest filing identifies LeonaBio, Inc. by CUSIP 04746L203 and gives its principal executive office as 18706 North Creek Parkway, Suite 104, Bothell, WA 98011 (SCHEDULE 13G, 2026-11-04).
What the percentages are based on
The percentages set forth herein are calculated based upon 9,421,663 shares of Common Stock outstanding as of August 12, 2026 as reported in the firm's 2nd Quarter 2026 Form 10Q filed on August 14, 2026.Anders Hove, SCHEDULE 13G/A, 2026-08-20
Source of funds (Item 3)
As contemplated in the original Schedule 13D filing, the prefunded warrant providing for the right to acquire 5,502,402 shares of Issuer's common stock was exercised, in part, on 10/26/2026 for the purchase and issuance of 3,149,470 shares of Issuer. The balance of the prefunded warrant was assigned to Perceptive Xontogeny Venture Fund 11, LP ("PXV II") as a distribution in kind pursuant to the previously disclosed distribution of securities to owners of Sermonix's common stock, and a new prefunded warrant for the remaining 2,352,932 common shares was issued to PXV II.Sermonix Pharmaceuticals, Inc., SCHEDULE 13D/A, 2026-10-28
Purpose of Transaction (Item 4)
Sermonix Pharmaceuticals, Inc.
The assignment of the remaining prefunded warrant rights to acquire 2,352,932 common shares of Issuer effects the previously disclosed distribution-in-kind to PXV II as part of the plan of distribution to the owners of Sermonix's common stock as described in the original Schedule 13D and Item 5.Item 4 of the SCHEDULE 13D/A filed 2026-10-28
Timeline
| Filed | Holder | Percent | Filing |
|---|---|---|---|
| 2025-10-10 | Oliveira Steven Michael | 4.09% | SCHEDULE 13G/A |
| 2025-11-14 | Baselake Partners, LP | 5% | SCHEDULE 13G |
| 2025-12-18 | BML Investment Partners, L.P. | 0% | SCHEDULE 13G/A |
| 2025-12-22 | Perceptive Advisors LLC | 13.9% | SCHEDULE 13D/A |
| 2025-12-23 | Perceptive Advisors LLC | 20.1% | SCHEDULE 13D/A |
| 2025-12-23 | Anders Hove | 5.2% | SCHEDULE 13G |
| 2026-01-08 | Anders Hove | 6.2% | SCHEDULE 13G/A |
| 2026-01-16 | Perceptive Advisors LLC | 19.99% | SCHEDULE 13D/A |
| 2026-02-06 | Baselake Partners, LP | 1.9% | SCHEDULE 13G/A |
| 2026-05-07 | Perceptive Advisors LLC | 19.99% | SCHEDULE 13D/A |
| 2026-05-15 | ADAR1 Capital Management, LLC | 7.7% | SCHEDULE 13G |
| 2026-08-20 | Anders Hove | 12.1% | SCHEDULE 13G/A |
| 2026-08-25 | Perceptive Advisors LLC | 19.99% | SCHEDULE 13D/A |
| 2026-08-31 | Sermonix Pharmaceuticals, Inc. | 36.9% | SCHEDULE 13D |
| 2026-10-26 | Perceptive Advisors LLC | 19.99% | SCHEDULE 13D/A |
| 2026-10-28 | Sermonix Pharmaceuticals, Inc. | 25.1% | SCHEDULE 13D/A |
| 2026-11-04 | Great Point Partners, LLC | 5.03% | SCHEDULE 13G |
Questions about who owns LeonaBio, Inc.
Who owns LeonaBio, Inc.?
On this page, 5 holders' latest ownership filings report 5% or more of LeonaBio, Inc.: Sermonix Pharmaceuticals, Inc. (25.1%, Schedule 13D/A, filed 2026-10-28), Perceptive Advisors LLC (19.99%, Schedule 13D/A, filed 2026-10-26), Anders Hove (12.1%, Schedule 13G/A, filed 2026-08-20), ADAR1 Capital Management, LLC (7.7%, Schedule 13G, filed 2026-05-15) and Great Point Partners, LLC (5.03%, Schedule 13G, filed 2026-11-04).
Who are the largest shareholders of LeonaBio, Inc.?
By the share each holder's latest filing reports, the largest holders of LeonaBio, Inc. on this page are Sermonix Pharmaceuticals, Inc. (25.1%), Perceptive Advisors LLC (19.99%) and Anders Hove (12.1%).
When did Sermonix Pharmaceuticals, Inc. buy into LeonaBio, Inc.?
The filings give report dates, not purchase dates. The earliest filing from Sermonix Pharmaceuticals, Inc. on this page is the Schedule 13D, filed 2026-08-31, reporting 36.9%; its latest, Schedule 13D/A filed 2026-10-28, reports 25.1%.
Is this an audit or a full list?
Neither. The ownership list on this page covers only Schedule 13D and 13G filings, which holders make once they own 5% or more of a class of shares (an amendment can report a stake that has since fallen below 5%); 17 such filings are shown here. It is not an audit and not a full cap table: holders who never reached 5% are not listed, and a stake can change after its latest filing.
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Where this comes from
Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.
Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.
