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5%+ stakes · Schedule 13D and 13G

Alto Neuroscience, Inc.: 5%+ holders

Who has reported owning 5% or more of Alto Neuroscience, Inc., from Schedule 13D and 13G filings: each holder's stake as filed, the timeline, and the purpose each 13D states, quoted.

At 5% or more5
Filings20
Latest filing2026-08-14

Alto Neuroscience, Inc. has 20 Schedule 13D or 13G filings on record since 2025-07-16. 5 holders' latest filing reports 5% or more of common stock, $0.0001 par value per share. Each figure below is the holder's own, as filed, with the filing linked.

Holders

HolderPercentSharesLatestEvent date
Perceptive Advisors LLC9.99%4,176,711SCHEDULE 13G/A, 2026-08-142026-06-30
Commodore Capital LP9.9%3,588,180SCHEDULE 13G/A, 2026-05-152026-03-31
Sirenia Capital Management LP6.2%2,219,568SCHEDULE 13G/A, 2026-08-142026-06-30
BlackRock, Inc.6%2,104,406SCHEDULE 13G, 2026-07-272026-06-30
EcoR1 Capital, LLC5.8%2,232,000SCHEDULE 13G, 2026-07-202026-07-13
Armistice Capital, LLC4.94%1,536,000SCHEDULE 13G/A, 2026-02-182025-12-31
Steven A. Cohen3.7%1,170,865SCHEDULE 13G/A, 2026-05-152026-03-31
K2 HealthVentures Equity Trust LLC2.4%788,995SCHEDULE 13G/A, 2026-02-172025-12-31
Vestal Point Capital, LP2.2%785,000SCHEDULE 13G/A, 2026-08-142026-06-30

Timeline

FiledHolderPercentFiling
2025-07-16BlackRock, Inc.2.1%SCHEDULE 13G/A
2025-08-14Armistice Capital, LLC6%SCHEDULE 13G/A
2025-10-10Perceptive Advisors LLC7.3%SCHEDULE 13G
2025-10-27Commodore Capital LP9.8%SCHEDULE 13G
2026-02-17Vestal Point Capital, LP8%SCHEDULE 13G
2026-02-17Steven A. Cohen8.9%SCHEDULE 13G/A
2026-02-17K2 HealthVentures Equity Trust LLC2.4%SCHEDULE 13G/A
2026-02-17Armistice Capital, LLC6%SCHEDULE 13G/A
2026-02-17Perceptive Advisors LLC9.99%SCHEDULE 13G/A
2026-02-17Commodore Capital LP9.9%SCHEDULE 13G/A
2026-02-18Armistice Capital, LLC4.94%SCHEDULE 13G/A
2026-05-15Vestal Point Capital, LP6.5%SCHEDULE 13G/A
2026-05-15Sirenia Capital Management LP7.9%SCHEDULE 13G
2026-05-15Steven A. Cohen3.7%SCHEDULE 13G/A
2026-05-15Commodore Capital LP9.9%SCHEDULE 13G/A
2026-07-20EcoR1 Capital, LLC5.8%SCHEDULE 13G
2026-07-27BlackRock, Inc.6%SCHEDULE 13G
2026-08-14Vestal Point Capital, LP2.2%SCHEDULE 13G/A
2026-08-14Sirenia Capital Management LP6.2%SCHEDULE 13G/A
2026-08-14Perceptive Advisors LLC9.99%SCHEDULE 13G/A

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Where this comes from

Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.

Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.

Cite this page

Permanent URL: https://mentionfox.com/stakes/alto-neuroscience
Last updated 2026-09-27
Primary record: SEC filing 1 · SEC filing 2 · SEC filing 3 · SEC filing 4
Alto Neuroscience, Inc. 5%+ holders: 5 at 5% or more, largest Perceptive Advisors LLC 9.99%. MentionFox, 2026-09-27. https://mentionfox.com/stakes/alto-neuroscience