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5%+ stakes · Schedule 13D and 13G

enGene Holdings Inc.: 5%+ holders

Before you sign with, sell to or invest in enGene Holdings Inc.

MentionFox check on enGene Holdings Inc.: no red flags found in 21 sources; 1 item to note (checked 7 November 2026). mentionfox.com/c/stakes/engene-holdings

  • Note: Layoff plan disclosed Jun 2026 (filing)

Check enGene Holdings Inc. before you sign, sell or invest Free, no sign-up: every record on file, each linked to its source.

What do you want to do about enGene Holdings Inc.?

Who has reported owning 5% or more of enGene Holdings Inc., from Schedule 13D and 13G filings: each holder's stake as filed, the timeline, and the purpose each 13D states, quoted.

As of November 7, 2026, 4 holders' latest Schedule 13D or 13G filings report owning 5% or more of enGene Holdings Inc. The largest reported stake is Perceptive Advisors LLC's, at 9.99%. 17 filings are on record since November 14, 2025 (Schedule 13G/A, August 14, 2026).

ACORN BIOVENTURES, L.P. also filed stake reports on 5 other companies ↓

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Key facts

  • · Reporting person: Perceptive Advisors LLC · Sole voting: 0 · Shared voting: 6,899,803 · Sole dispositive: 0 · Shared dispositive: 6,899,803 · SCHEDULE 13G/A, 2026-08-14
  • · Reporting person: Deep Track Capital, LP · Sole voting: 0 · Shared voting: 0 · Sole dispositive: 0 · Shared dispositive: 0 · SCHEDULE 13G/A, 2026-08-14
  • · Reporting person: Venrock Healthcare Capital Partners III, L.P. · Sole voting: 0 · Shared voting: 0 · Sole dispositive: 0 · Shared dispositive: 0 · SCHEDULE 13G/A, 2026-08-14
  • · Reporting person: Invus Public Equities, L.P. · Sole voting: 5,481,984 · Shared voting: 0 · Sole dispositive: 5,481,984 · Shared dispositive: 0 · SCHEDULE 13G/A, 2026-08-13
  • · Reporting person: Blue Owl Capital Holdings LP · Sole voting: 511,177 · Shared voting: 0 · Sole dispositive: 511,177 · Shared dispositive: 0 · SCHEDULE 13G/A, 2026-08-12
At 5% or more4
Filings17
Latest filing2026-08-14

enGene Holdings Inc. has 17 Schedule 13D or 13G filings on record since 2025-11-14. 4 holders' latest filing reports 5% or more of common shares. Each figure below is the holder's own, as filed, with the filing linked.

Layoffs on record: 2 filings or notices, latest 2026-06-18 (layoff filings and notices).

Holders

HolderPercentSharesLatestEvent date
Perceptive Advisors LLC9.99%6,899,803SCHEDULE 13G/A, 2026-08-142026-06-30
BML Investment Partners, L.P.9.95%6,669,908SCHEDULE 13G/A, 2026-05-142026-05-12
9.3%6,256,662SCHEDULE 13G/A, 2026-08-132026-06-30
5%3,357,282SCHEDULE 13G, 2026-07-222026-07-20
Kynam Capital Management, LP2.23%1,492,898SCHEDULE 13G/A, 2026-02-172025-12-31
Blue Owl Capital Holdings LP0.76%511,177SCHEDULE 13G/A, 2026-08-122026-06-30
Deep Track Capital, LP0%0SCHEDULE 13G/A, 2026-08-142026-06-30
Cormorant Asset Management, LP0%0SCHEDULE 13G/A, 2026-05-152026-03-31
Venrock Healthcare Capital Partners III, L.P.0%0SCHEDULE 13G/A, 2026-08-142026-06-30

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More on enGene Holdings Inc. and the records around it.

enGene Holdings Inc. elsewhere on the record

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Example from a real report (our sample on Target): “The Q2 2026 earnings report, published August 19, 2026, showed adjusted EPS of $2.46 against an expected $2.33” Source: CNBC

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What the Full Report on enGene Holdings Inc. covers

  1. The Short Answer

  2. Which Company This Is

  3. What They Do, And How The Money Works

  4. Who Runs It, And How To Reach Them

  5. The Money: Funding, Valuation, Runway

  6. Who Pays Them, And Who They Are Up Against

  7. Warning Bells

  8. Sources

    20 cited sources found

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Voting and dispositive power, as filed

Reporting personSole votingShared votingSole dispositiveShared dispositiveFiling
Perceptive Advisors LLC06,899,80306,899,803SCHEDULE 13G/A, 2026-08-14
Joseph Edelman06,899,80306,899,803SCHEDULE 13G/A, 2026-08-14
Perceptive Life Sciences Master Fund, Ltd.06,899,80306,899,803SCHEDULE 13G/A, 2026-08-14
Invus Public Equities, L.P.5,481,98405,481,9840SCHEDULE 13G/A, 2026-08-13
Invus Public Equities Advisors, LLC5,481,98405,481,9840SCHEDULE 13G/A, 2026-08-13
Invus Global Management, LLC5,481,98405,481,9840SCHEDULE 13G/A, 2026-08-13
Siren, L.L.C.5,481,98405,481,9840SCHEDULE 13G/A, 2026-08-13
Avicenna Life Sci Master Fund LP774,6780774,6780SCHEDULE 13G/A, 2026-08-13
Avicenna Life Sci Master GP LLC774,6780774,6780SCHEDULE 13G/A, 2026-08-13
Ulys, L.L.C.774,6780774,6780SCHEDULE 13G/A, 2026-08-13
Raymond Debbane6,256,66206,256,6620SCHEDULE 13G/A, 2026-08-13
Acorn Bioventures, L.P.01,410,05901,410,059SCHEDULE 13G, 2026-07-22
Acorn Capital Advisors Gp, LLC01,410,05901,410,059SCHEDULE 13G, 2026-07-22
Acorn Bioventures 2, L.P.01,947,22301,947,223SCHEDULE 13G, 2026-07-22
Acorn Capital Advisors GP 2, LLC01,947,22301,947,223SCHEDULE 13G, 2026-07-22
Anders Hove03,357,28203,357,282SCHEDULE 13G, 2026-07-22
Blue Owl Capital Holdings LP511,1770511,1770SCHEDULE 13G/A, 2026-08-12
Deep Track Capital, LP0000SCHEDULE 13G/A, 2026-08-14
Deep Track Biotechnology Master Fund, Ltd.0000SCHEDULE 13G/A, 2026-08-14
David Kroin0000SCHEDULE 13G/A, 2026-08-14
Venrock Healthcare Capital Partners III, L.P.0000SCHEDULE 13G/A, 2026-08-14
VHCP Co-Investment Holdings III, LLC0000SCHEDULE 13G/A, 2026-08-14
Venrock Healthcare Capital Partners EG, L.P.0000SCHEDULE 13G/A, 2026-08-14
VHCP Management III, LLC0000SCHEDULE 13G/A, 2026-08-14

The latest filing identifies enGene Holdings Inc. by CUSIP 29286M105 and gives its principal executive office as 4868 Rue Levy, Suite 220, Saint-Laurent (SCHEDULE 13G/A, 2026-08-14).

What the percentages are based on

As of June 30, 2026, each of the Reporting Persons may be deemed to be the beneficial owner of the percentage of Shares listed on such Reporting Person's cover page.Raymond Debbane, SCHEDULE 13G/A, 2026-08-13
The percentages set forth herein are calculated based upon 66,989,466 shares of Common Stock outstanding as of June 9, 2026 as reported in the Issuer's Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2026 filed with the Securities and Exchange Commission on June 15, 2026..Anders Hove, SCHEDULE 13G, 2026-07-22

Timeline

FiledHolderPercentFiling
2025-11-14Deep Track Capital, LP4.37%SCHEDULE 13G/A
2025-11-18Deep Track Capital, LP6.69%SCHEDULE 13G
2025-11-18Perceptive Advisors LLC9.99%SCHEDULE 13G
2026-01-27Raymond Debbane6.3%SCHEDULE 13G
2026-02-17Cormorant Asset Management, LP5.97%SCHEDULE 13G
2026-02-17Venrock Healthcare Capital Partners III, L.P.7.1%SCHEDULE 13G/A
2026-02-17Kynam Capital Management, LP2.23%SCHEDULE 13G/A
2026-05-05Raymond Debbane7.8%SCHEDULE 13G/A
2026-05-13BML Investment Partners, L.P.7.8%SCHEDULE 13G
2026-05-14BML Investment Partners, L.P.9.95%SCHEDULE 13G/A
2026-05-15Cormorant Asset Management, LP0%SCHEDULE 13G/A
2026-07-22Anders Hove5%SCHEDULE 13G
2026-08-12Blue Owl Capital Holdings LP0.76%SCHEDULE 13G/A
2026-08-13Raymond Debbane9.3%SCHEDULE 13G/A
2026-08-14Deep Track Capital, LP0%SCHEDULE 13G/A
2026-08-14Perceptive Advisors LLC9.99%SCHEDULE 13G/A
2026-08-14Venrock Healthcare Capital Partners III, L.P.0%SCHEDULE 13G/A

Questions about who owns enGene Holdings Inc.

Who owns enGene Holdings Inc.?

On this page, 4 holders' latest ownership filings report 5% or more of enGene Holdings Inc.: Perceptive Advisors LLC (9.99%, Schedule 13G/A, filed 2026-08-14), BML Investment Partners, L.P. (9.95%, Schedule 13G/A, filed 2026-05-14), Raymond Debbane (9.3%, Schedule 13G/A, filed 2026-08-13) and Anders Hove (5%, Schedule 13G, filed 2026-07-22).

Who are the largest shareholders of enGene Holdings Inc.?

By the share each holder's latest filing reports, the largest holders of enGene Holdings Inc. on this page are Perceptive Advisors LLC (9.99%), BML Investment Partners, L.P. (9.95%) and Raymond Debbane (9.3%).

When did Perceptive Advisors LLC buy into enGene Holdings Inc.?

The filings give report dates, not purchase dates. The earliest filing from Perceptive Advisors LLC on this page is the Schedule 13G, filed 2025-11-18, reporting 9.99%; its latest, Schedule 13G/A filed 2026-08-14, reports 9.99%.

Is this an audit or a full list?

Neither. The ownership list on this page covers only Schedule 13D and 13G filings, which holders make once they own 5% or more of a class of shares (an amendment can report a stake that has since fallen below 5%); 17 such filings are shown here. It is not an audit and not a full cap table: holders who never reached 5% are not listed, and a stake can change after its latest filing.

Also on the record for enGene Holdings Inc.

DateRecordFigureOur pageSource
July 16, 2026Leadership change: Richard Glickman departs, Director—Leadership changesSource
June 15, 2026Leadership change: Hussein Sweiti departs, Chief Medical Officer—Leadership changesSource

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Where this comes from

Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.

Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.

Cite this page

Permanent URL: https://mentionfox.com/stakes/engene-holdings
Last updated 2026-11-07
Primary record: SEC filing 1 · SEC filing 2 · SEC filing 3 · SEC filing 4
Who owns 5% or more of enGene Holdings Inc.? 4 holders at 5% or more, largest Perceptive Advisors LLC 9.99%. MentionFox, 2026-11-07. https://mentionfox.com/stakes/engene-holdings