As of November 10, 2026, 50 biotech companies in Philadelphia have filed a new SEC Form D on record, reporting $776.32M sold. 2 filed in the last 90 days, against 4 in the 90 days before. The biggest raise on record here is Eliem Therapeutics, Inc., at $120M (SEC Form D, September 11, 2026).
2 biotech companies in Philadelphia filed in the last 90 days, against 4 in the 90 days before. The biggest raise on record here is Eliem Therapeutics, Inc. at $120M.
On the record Pennsylvania layoffs by employer
Companies raising per week
The last 90 days
| Based | People named | |||
|---|---|---|---|---|
| Aposture Surgical Corp first filing | $87K | 2026-08-13 | Philadelphia, PA | John Chung, Kyung Woo Park |
| Amplica Bio, Inc. first filing | $30K | 2026-09-11 | Wilmington, DE | Kush Mehta, Kaustav Gopinathan |
First-time filers, last 90 days
Aposture Surgical Corp, Amplica Bio, Inc..
Everything on record
| Based | People named | |||
|---|---|---|---|---|
| Eliem Therapeutics, Inc. first filing | $120M | 2024-07-02 | Wilmington, DE | Aoife Brennan, Andrew Levin +6 |
| ArriVent Biopharma, Inc. first filing | $110M | 2022-12-29 | Newtown Square, PA | Zhengbin (Bing) Yao, Cong Xu +5 |
| Castle Creek Biosciences, Inc. first filing | $75M | 2025-02-25 | Exton, PA | Matthew Gantz, Jude Sullivan +6 |
| SYNNOVATION THERAPEUTICS, INC. | $69.87M | 2023-12-14 | Wilmington, DE | Wenqing Yao, Liangxing Wu +2 |
| FORE US Bio Inc. first filing | $62.08M | 2023-08-24 | Philadelphia, PA | Matthew Ros, Erez Chimovits +8 |
| Interius BioTherapeutics, Inc. | $51.43M | 2024-06-03 | Philadelphia, PA | Philip Johnson, M.D., Dora Mitchell +4 |
| Eliem Therapeutics, Inc. first filing | $41.87M | 2024-07-02 | Wilmington, DE | Aoife Brennan, Andrew Levin +6 |
| FORE US Bio Inc. | $37.44M | 2025-05-15 | Philadelphia, PA | William Hinshaw, Erez Chimovits +6 |
| SYNNOVATION THERAPEUTICS, INC. first filing | $25M | 2023-05-24 | Wilmington, DE | Wenqing Yao, Liangxing Wu +2 |
| Interius BioTherapeutics, Inc. first filing | $21.45M | 2023-10-20 | Philadelphia, PA | Philip Johnson, Dora Mitchell +3 |
| Neuraptive Therapeutics, Inc. first filing | $19.49M | 2022-10-14 | Philadelphia, PA | Robert Radie, Evan Tzanis +5 |
| Tolerance Bio Inc. first filing | $15.10M | 2026-06-18 | Philadelphia, PA | Francisco Leon, Justin Vogel +4 |
| Chimeron Bio Corp | $13.74M | 2025-03-03 | Philadelphia, PA | Kevin Heyeck, Monica Coleman +2 |
| VITARA BIOMEDICAL, INC. | $10M | 2024-10-28 | Philadelphia, PA | Thomas Todorow, Diem Nguyen +4 |
| Palvella Therapeutics, Inc. first filing | $9.70M | 2022-12-30 | Wayne, PA | Wesley Kaupinen, Scott Morenstein +7 |
| Praeventix, Inc. | $6.81M | 2025-05-20 | Exton, PA | Douglas Pippin, Leonard Moulder, Jr. +2 |
| ImmunoGenesis, Inc. | $5.75M | 2025-01-15 | Doylestown, PA | Jennifer Barlow, Ted Koutouzis +4 |
| Metabolics Pharma, Inc. first filing | $5.53M | 2024-09-19 | Philadelphia, PA | Richard Larson, Jay Brammer +4 |
| ThirdLaw Molecular, Inc. first filing | $5.50M | 2025-10-08 | Blue Bell, PA | Christian Schafmeister, Eric Heil +2 |
| SwitchPoint Bio Holding, Inc. first filing | $5.27M | 2026-03-10 | Wilmington, DE | Samuel Myllykangas, Jussi Paananen +1 |
| Enterin, Inc. first filing | $5.10M | 2023-12-06 | Philadelphia, PA | David McCullough, Michael Zasloff +9 |
| BlueWhale Bio, Inc. first filing | $5M | 2025-10-16 | Philadelphia, PA | Peter Keller, Paula Cannon +3 |
| Avstera Therapeutics Corp. first filing | $5M | 2023-10-03 | Malvern, PA | Ajay Raju |
| GENEOS Therapeutics, Inc. first filing | $5M | 2023-04-13 | Plymouth Meeting, PA | Niranjan Sardesai, James Eadie +5 |
| Peptaris, Inc. first filing | $4M | 2026-06-16 | Philadelphia, PA | Francis Herbert, Rajendra Singh |
| GPN VACCINES, INC. first filing | $3.50M | 2026-01-28 | Wilmington, DE | Timothy Hirst, James Selkirk |
| NRX Pharmaceuticals, Inc. first filing | $3.50M | 2025-03-07 | Wilmington, DE | Jonathan Javitt, Michael Abrams +4 |
| Aprea Therapeutics, Inc. first filing | $3.06M | 2025-12-29 | Doylestown, PA | Oren Gilad, John Hamill +8 |
| Prolifagen, Inc. first filing | $3.03M | 2025-09-23 | Doylestown, PA | Claudine Bruck, Michael Behr +3 |
| Praeventix, Inc. | $3M | 2026-02-13 | Exton, PA | Douglas Pippin, PhD, Leon Moulder +2 |
| Aevumed Inc. first filing | $3M | 2025-06-12 | Malvern, PA | Saif Khalil, William Shopoff +1 |
| Xenagos Bio, Inc. first filing | $2.52M | 2026-05-15 | Philadelphia, PA | Michael McElhaugh, Abel De La Rosa +1 |
| Praeventix, Inc. first filing | $2.32M | 2022-11-08 | Exton, PA | Douglas Pippin, Leon Moulder, Jr. |
| EOLO USA, Inc. first filing | $1.80M | 2023-02-08 | Wilmington, DE | Maria Nunez, Gerardo Marchesini +2 |
| Protein Dynamic Solutions, Inc. first filing | $1.77M | 2025-11-07 | Wilmington, DE | Jose Casellas, Belinda Pastrana +3 |
| Aevumed Inc. first filing | $1.50M | 2025-06-12 | Malvern, PA | Saif Khalil |
| Phio Pharmaceuticals Corp. | $1.42M | 2025-11-12 | King Of Prussia, PA | Robert Bitterman, Patricia Bradford +4 |
| Chimeron Bio Corp first filing | $1.20M | 2022-11-30 | Philadelphia, PA | Kevin Heyeck, Thimmaiah Chendrimada +3 |
| StimuSIL, Inc. | $1.10M | 2024-05-10 | Wilmington, DE | Ana Villalba Villar, Pablo Villalba +1 |
| Annovis Bio, Inc. first filing | $1.06M | 2023-04-25 | Berwyn, PA | Maria Maccecchini, Michael Hoffman +4 |
| RheoTek Medical LLC first filing | $1.06M | 2023-09-12 | Philadelphia, PA | Daniel Mazzaferro, Steven Schultz +1 |
| Toby, Inc. | $815K | 2025-07-15 | Wilmington, DE | Matthew Laskowski, Dragan Sebisanovic +3 |
| Moberg Analytics Inc first filing | $600K | 2025-10-29 | Philadelphia, PA | Richard Moberg |
| Toby, Inc. first filing | $600K | 2025-02-04 | Wilmington, DE | Matthew Laskowski, Dragan Sebisanovic |
| StimuSIL, Inc. | $600K | 2025-03-07 | Wilmington, DE | Ana Villalba Villar, Pablo Villalba +1 |
| BioLattice Ophthalmics, Inc, first filing | $575K | 2026-03-30 | Philadelphia, PA | Linda Alunkal, Amelia Zellander +1 |
| Amplifi Vascular, Inc. first filing | $558K | 2023-08-21 | Wilmington, DE | Sean Morris, Nathaniel Hagedorn +1 |
| BioCurie, Inc. first filing | $500K | 2025-06-12 | Wilmington, DE | Irene Romble, Richard Braatz +3 |
| Trevarx Biomedical, Inc. first filing | $350K | 2025-08-04 | Philadelphia, PA | Jean Cho |
| Aevumed Inc. first filing | $305K | 2025-06-12 | Malvern, PA | Saif Khalil |
| NK-One Therapeutics, Inc. first filing | $290K | 2026-04-27 | Wayne, PA | Michael Shine, Marco Pappagallo |
| Aevumed Inc. first filing | $264K | 2025-06-12 | Malvern, PA | Saif Khalil |
| Phio Pharmaceuticals Corp. | $232K | 2025-08-04 | King Of Prussia, PA | Robert Bitterman, Patricia Bradford +5 |
| ImCare Biotech, Inc. first filing | $153K | 2023-07-14 | Doylestown, PA | Aaron Lu, Xuanyong Lu, PhD +3 |
| Gnosko Bio Inc. first filing | $100K | 2024-07-01 | Wayne, PA | William Wendel, Sam Agris +2 |
| Biophysical Therapeutics, Inc. first filing | $100K | 2023-06-07 | Wilmington, DE | Forrest Michael |
| Aposture Surgical Corp first filing | $87K | 2026-08-13 | Philadelphia, PA | John Chung, Kyung Woo Park |
| Merlin Biotech, Inc. first filing | $50K | 2026-08-11 | Doylestown, PA | Randall Hyer, Carol Brosgart +4 |
| GENIE Therapeutics, Inc. first filing | $50K | 2023-07-27 | Wilmington, DE | Aaron Tabor |
| StimuSIL, Inc. first filing | $49K | 2023-09-13 | Wilmington, DE | Ana Villalba Villar, Pablo Villalba +1 |
| Biophysical Therapeutics, Inc. | $35K | 2023-08-21 | Wilmington, DE | Forrest Michael |
| Amplica Bio, Inc. first filing | $30K | 2026-09-11 | Wilmington, DE | Kush Mehta, Kaustav Gopinathan |
| NEUROPATHIX, INC. first filing | — | 2025-11-17 | Doylestown, PA | Dean Petkanas |
| Mid-Atlantic BioTherapeutics, Inc. first filing | — | 2024-09-30 | Doylestown, PA | David Jobes, David Horn +4 |
| REVNA BIOSCIENCES, INC. first filing | — | 2024-12-31 | Horsham, PA | Derrick Akpalu |
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How this list is built
Every company here filed a Form D with the SEC from this sector and metro. A Form D is the notice a company files when it sells shares or other securities without a public offering, so it catches seed rounds, small rounds and rounds that were never announced, alongside the large ones that make the news. Only new offerings by operating companies count: amendments, pooled investment funds, real estate vehicles and special purpose vehicles are left out, so each row is a company raising money for itself.
The amount shown is the total the filing reports as sold so far. Some filings report nothing sold yet; those rows show a dash and add nothing to the totals. "First filing" marks a company whose first Form D on record this is. Each company links to our page for the filing, or to the SEC's own copy, and the list can be copied as CSV for a spreadsheet.
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