As of November 7, 2026, 6 holders' latest Schedule 13D or 13G filings report owning 5% or more of Xencor Inc. The largest reported stake is BlackRock, Inc.'s, at 14.5%. 17 filings are on record since July 29, 2025 (Schedule 13G/A, October 27, 2026).
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Key facts
- · Reporting person: Primecap Management Co · Sole voting: 9,879,855 · Shared voting: 0 · Sole dispositive: 9,879,855 · Shared dispositive: 0 · SCHEDULE 13G/A, 2026-11-06
- · Reporting person: Vanguard Capital Management · Sole voting: 507,754 · Shared voting: 0 · Sole dispositive: 3,710,894 · Shared dispositive: 0 · SCHEDULE 13G/A, 2026-10-30
- · Reporting person: BlackRock, Inc. · Sole voting: 10,655,400 · Shared voting: 0 · Sole dispositive: 10,816,417 · Shared dispositive: 0 · SCHEDULE 13G/A, 2026-10-27
- · Holder: Vanguard Capital Management · Percent: 5.13% · SCHEDULE 13G
- · Holder: EcoR1 Capital, LLC · Percent: 2.9% · SCHEDULE 13G/A
Xencor Inc has 17 Schedule 13D or 13G filings on record since 2025-07-29. 6 holders' latest filing reports 5% or more of com. Each figure below is the holder's own, as filed, with the filing linked.
Holders
| Holder | Percent | Shares | Latest | Event date |
|---|---|---|---|---|
| BlackRock, Inc. | 14.5% | 10,816,417 | SCHEDULE 13G/A, 2026-10-27 | 2026-09-30 |
| Primecap Management Co | 13.29% | 9,879,855 | SCHEDULE 13G/A, 2026-11-06 | 2026-09-30 |
| Bvf Partners L P | 9.99% | 7,133,720 | SCHEDULE 13G/A, 2026-02-17 | 2025-12-31 |
| RTW Investments, LP | 8.7% | 6,221,054 | SCHEDULE 13G, 2025-11-14 | 2025-09-30 |
| RA Capital Management, L.P. | 6.5% | 4,736,739 | SCHEDULE 13G, 2026-03-30 | 2026-03-23 |
| State Street Corporation | 6.3% | 4,507,254 | SCHEDULE 13G, 2026-02-09 | 2025-12-31 |
| Vanguard Capital Management | 4.99% | 3,710,894 | SCHEDULE 13G/A, 2026-10-30 | 2026-09-30 |
| EcoR1 Capital, LLC | 2.9% | 2,183,000 | SCHEDULE 13G/A, 2026-05-15 | 2026-03-31 |
| T. Rowe Price Associates, Inc. | 2.4% | 1,693,292 | SCHEDULE 13G/A, 2025-11-14 | 2025-09-30 |
| The Vanguard Group | 0% | 0 | SCHEDULE 13G/A, 2026-03-27 | 2026-03-13 |
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Keep reading
More on Xencor Inc and the records around it.
Xencor Inc elsewhere on the record
Companies that share a holder
- EcoR1 Capital, LLC also filed stake reports on 20 other companies: Mereo BioPharma Group plc (Aug 2026), Alto Neuroscience, Inc. (Jul 2026), Fulcrum Therapeutics, Inc. (Jun 2026)
- PRIMECAP MANAGEMENT CO/CA/ also filed stake reports on 24 other companies: GRAIL, Inc. (Nov 2026), MARKETAXESS HOLDINGS INC (Nov 2026), Pulmonx Corp (Nov 2026)
- RTW Investments, LP also filed stake reports on 43 other companies: CG Oncology, Inc. (Aug 2026), iRhythm Holdings, Inc. (Aug 2026), Kailera Therapeutics, Inc. (Aug 2026)
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Voting and dispositive power, as filed
| Reporting person | Sole voting | Shared voting | Sole dispositive | Shared dispositive | Filing |
|---|---|---|---|---|---|
| BlackRock, Inc. | 10,655,400 | 0 | 10,816,417 | 0 | SCHEDULE 13G/A, 2026-10-27 |
| Primecap Management Co | 9,879,855 | 0 | 9,879,855 | 0 | SCHEDULE 13G/A, 2026-11-06 |
| Vanguard Capital Management | 507,754 | 0 | 3,710,894 | 0 | SCHEDULE 13G/A, 2026-10-30 |
The latest filing identifies Xencor Inc by CUSIP 98401F105 and gives its principal executive office as 465 N. HALSTEAD ST., SUITE 200, PASADENA, CA 91107 (SCHEDULE 13G/A, 2026-11-06).
Timeline
| Filed | Holder | Percent | Filing |
|---|---|---|---|
| 2025-07-29 | The Vanguard Group | 12.11% | SCHEDULE 13G/A |
| 2025-08-14 | Primecap Management Co | 14.79% | SCHEDULE 13G/A |
| 2025-10-17 | Bvf Partners L P | 6.5% | SCHEDULE 13G |
| 2025-10-31 | The Vanguard Group | 9.95% | SCHEDULE 13G/A |
| 2025-11-14 | T. Rowe Price Associates, Inc. | 2.4% | SCHEDULE 13G/A |
| 2025-11-14 | RTW Investments, LP | 8.7% | SCHEDULE 13G |
| 2025-12-03 | The Vanguard Group | 10.03% | SCHEDULE 13G/A |
| 2026-02-09 | State Street Corporation | 6.3% | SCHEDULE 13G |
| 2026-02-17 | Bvf Partners L P | 9.99% | SCHEDULE 13G/A |
| 2026-02-17 | EcoR1 Capital, LLC | 6.4% | SCHEDULE 13G/A |
| 2026-03-27 | The Vanguard Group | 0% | SCHEDULE 13G/A |
| 2026-03-30 | RA Capital Management, L.P. | 6.5% | SCHEDULE 13G |
| 2026-05-15 | EcoR1 Capital, LLC | 2.9% | SCHEDULE 13G/A |
| 2026-07-31 | Vanguard Capital Management | 5.13% | SCHEDULE 13G |
| 2026-10-27 | BlackRock, Inc. | 14.5% | SCHEDULE 13G/A |
| 2026-10-30 | Vanguard Capital Management | 4.99% | SCHEDULE 13G/A |
| 2026-11-06 | Primecap Management Co | 13.29% | SCHEDULE 13G/A |
Questions about who owns Xencor Inc
Who owns Xencor Inc?
On this page, 6 holders' latest ownership filings report 5% or more of Xencor Inc: BlackRock, Inc. (14.5%, Schedule 13G/A, filed 2026-10-27), Primecap Management Co (13.29%, Schedule 13G/A, filed 2026-11-06), Bvf Partners L P (9.99%, Schedule 13G/A, filed 2026-02-17), RTW Investments, LP (8.7%, Schedule 13G, filed 2025-11-14) and RA Capital Management, L.P. (6.5%, Schedule 13G, filed 2026-03-30); 1 more is listed above.
Who are the largest shareholders of Xencor Inc?
By the share each holder's latest filing reports, the largest holders of Xencor Inc on this page are BlackRock, Inc. (14.5%), Primecap Management Co (13.29%) and Bvf Partners L P (9.99%).
When did BlackRock, Inc. buy into Xencor Inc?
The filings give report dates, not purchase dates. The earliest filing from BlackRock, Inc. on this page is the Schedule 13G/A, filed 2026-10-27, reporting 14.5%. That earliest filing is itself an amendment, which updates an earlier report.
Is this an audit or a full list?
Neither. The ownership list on this page covers only Schedule 13D and 13G filings, which holders make once they own 5% or more of a class of shares (an amendment can report a stake that has since fallen below 5%); 17 such filings are shown here. It is not an audit and not a full cap table: holders who never reached 5% are not listed, and a stake can change after its latest filing.
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Where this comes from
Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.
Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.