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5%+ stakes · Schedule 13D and 13G

Fulcrum Therapeutics, Inc.: 5%+ holders

Who has reported owning 5% or more of Fulcrum Therapeutics, Inc., from Schedule 13D and 13G filings: each holder's stake as filed, the timeline, and the purpose each 13D states, quoted.

At 5% or more7
Filings19
Latest filing2026-08-14

Fulcrum Therapeutics, Inc. has 19 Schedule 13D or 13G filings on record since 2025-08-12. 7 holders' latest filing reports 5% or more of common stock, $0.001 par value per share. Each figure below is the holder's own, as filed, with the filing linked.

Holders

HolderPercentSharesLatestEvent date
Tang Capital Management, LLC10.4%6,913,329SCHEDULE 13G/A, 2026-07-152026-07-13
EcoR1 Capital, LLC9%6,000,000SCHEDULE 13G, 2026-06-252026-06-17
Nantahala Capital Management, LLC8.22%5,475,040SCHEDULE 13G, 2026-08-142026-06-30
BlackRock, Inc.7.2%4,802,880SCHEDULE 13G/A, 2026-07-282026-06-30
Bank Of America Corp6.7%4,468,123SCHEDULE 13G, 2026-08-032026-06-30
BlackRock Portfolio Management LLC6%4,021,379SCHEDULE 13G, 2026-07-172026-06-30
Montanova Capital, LLC5.5%3,680,921SCHEDULE 13G/A, 2026-08-142026-06-30
Adage Capital Management, L.P.4.5%2,432,000SCHEDULE 13G/A, 2025-11-132025-09-30
RA Capital Management, L.P.0%0SCHEDULE 13G/A, 2026-08-142026-06-30
The Vanguard Group0%0SCHEDULE 13G/A, 2026-03-262026-03-13
TCG Crossover GP II, LLC0%0SCHEDULE 13G/A, 2026-08-142026-06-30

Timeline

FiledHolderPercentFiling
2025-08-12Adage Capital Management, L.P.8.5%SCHEDULE 13G/A
2025-10-17BlackRock, Inc.6%SCHEDULE 13G/A
2025-11-13Adage Capital Management, L.P.4.5%SCHEDULE 13G/A
2025-12-10RA Capital Management, L.P.11.2%SCHEDULE 13G/A
2026-02-17RA Capital Management, L.P.9.9%SCHEDULE 13G/A
2026-03-26The Vanguard Group0%SCHEDULE 13G/A
2026-05-15Nantahala Capital Management, LLC4.58%SCHEDULE 13G/A
2026-05-15TCG Crossover GP II, LLC7.9%SCHEDULE 13G/A
2026-06-10Tang Capital Management, LLC8.2%SCHEDULE 13G
2026-06-25EcoR1 Capital, LLC9%SCHEDULE 13G
2026-06-25EcoR1 Capital, LLC9%SCHEDULE 13G
2026-07-15Tang Capital Management, LLC10.4%SCHEDULE 13G/A
2026-07-17BlackRock Portfolio Management LLC6%SCHEDULE 13G
2026-07-28BlackRock, Inc.7.2%SCHEDULE 13G/A
2026-08-03Bank Of America Corp6.7%SCHEDULE 13G
2026-08-14Montanova Capital, LLC5.5%SCHEDULE 13G/A
2026-08-14Nantahala Capital Management, LLC8.22%SCHEDULE 13G
2026-08-14TCG Crossover GP II, LLC0%SCHEDULE 13G/A
2026-08-14RA Capital Management, L.P.0%SCHEDULE 13G/A

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Where this comes from

Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.

Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.

Cite this page

Permanent URL: https://mentionfox.com/stakes/fulcrum-therapeutics
Last updated 2026-09-27
Primary record: SEC filing 1 · SEC filing 2 · SEC filing 3 · SEC filing 4
Fulcrum Therapeutics, Inc. 5%+ holders: 7 at 5% or more, largest Tang Capital Management, LLC 10.4%. MentionFox, 2026-09-27. https://mentionfox.com/stakes/fulcrum-therapeutics