As of November 8, 2026, 3 holders' latest Schedule 13D or 13G filings report owning 5% or more of uniQure N.V. The largest reported stake is Avoro Capital Advisors LLC's, at 9.87%. 24 filings are on record since July 31, 2025 (Schedule 13G/A, February 17, 2026).
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Key facts
- · Reporting person: Jpmorgan Chase & Co. · Sole voting: 5,654,307 · Shared voting: 1 · Sole dispositive: 5,943,150 · Shared dispositive: 1 · SCHEDULE 13G/A, 2026-10-16
- · Reporting person: RTW Investments, LP · Sole voting: 0 · Shared voting: 3,941,572 · Sole dispositive: 0 · Shared dispositive: 3,941,572 · SCHEDULE 13G, 2026-08-14
- · Reporting person: G1 Execution Services, LLC · Sole voting: 223 · Shared voting: 3,339,231 · Sole dispositive: 223 · Shared dispositive: 3,339,231 · SCHEDULE 13G/A, 2026-08-14
- · Reporting person: Aberdeen Group plc · Sole voting: 0 · Shared voting: 2,848,117 · Sole dispositive: 0 · Shared dispositive: 2,848,117 · SCHEDULE 13G/A, 2026-07-20
- · Holder: Jpmorgan Chase & Co · Percent: 7% · SCHEDULE 13G
uniQure N.V. has 24 Schedule 13D or 13G filings on record since 2025-07-31. 3 holders' latest filing reports 5% or more of ordinary shares, par value 0.05. Each figure below is the holder's own, as filed, with the filing linked.
Holders
| Holder | Percent | Shares | Latest | Event date |
|---|---|---|---|---|
| Avoro Capital Advisors LLC | 9.87% | 6,150,000 | SCHEDULE 13G/A, 2026-02-17 | 2025-12-31 |
| Jpmorgan Chase & Co. | 8.5% | 5,951,794 | SCHEDULE 13G/A, 2026-10-16 | 2026-09-30 |
| RTW Investments, LP | 5.7% | 3,941,572 | SCHEDULE 13G, 2026-08-14 | 2026-06-30 |
| G1 Execution Services, LLC | 4.8% | 3,339,231 | SCHEDULE 13G/A, 2026-08-14 | 2026-06-30 |
| Aberdeen Group plc | 4.52% | 2,848,117 | SCHEDULE 13G/A, 2026-07-20 | 2026-06-30 |
| Nantahala Capital Management, LLC | 3.75% | 2,051,852 | SCHEDULE 13G/A, 2025-08-14 | 2025-06-30 |
| State Street Corporation | 3.6% | 2,260,512 | SCHEDULE 13G, 2026-05-12 | 2026-03-31 |
| Fmr LLC | 2.8% | 1,743,808 | SCHEDULE 13G/A, 2026-05-06 | 2026-03-31 |
| Vestal Point Capital, LP | 0.4% | 225,000 | SCHEDULE 13G/A, 2025-11-14 | 2025-09-30 |
| EcoR1 Capital, LLC | 0% | 0 | SCHEDULE 13G/A, 2026-02-17 | 2025-12-31 |
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Keep reading
More on uniQure N.V. and the records around it.
uniQure N.V. elsewhere on the record
Companies that share a holder
- Aberdeen Group plc also filed stake reports on 12 other companies: Equillium, Inc. (Nov 2026), IMMUNIC, INC (Nov 2026), CODEXIS, INC. (Oct 2026)
- Avoro Capital Advisors LLC also filed stake reports on 18 other companies: Arrowhead Pharmaceuticals, Inc. (Aug 2026), Avalo Therapeutics, Inc. (Aug 2026), Hemab Therapeutics Holdings, Inc. (Aug 2026)
- EcoR1 Capital, LLC also filed stake reports on 20 other companies: Mereo BioPharma Group plc (Aug 2026), Alto Neuroscience, Inc. (Jul 2026), Fulcrum Therapeutics, Inc. (Jun 2026)
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Voting and dispositive power, as filed
| Reporting person | Sole voting | Shared voting | Sole dispositive | Shared dispositive | Filing |
|---|---|---|---|---|---|
| Jpmorgan Chase & Co. | 5,654,307 | 1 | 5,943,150 | 1 | SCHEDULE 13G/A, 2026-10-16 |
| RTW Investments, LP | 0 | 3,941,572 | 0 | 3,941,572 | SCHEDULE 13G, 2026-08-14 |
| Roderick Wong | 0 | 3,941,572 | 0 | 3,941,572 | SCHEDULE 13G, 2026-08-14 |
| G1 Execution Services, LLC | 223 | 3,339,231 | 223 | 3,339,231 | SCHEDULE 13G/A, 2026-08-14 |
| SIG Brokerage, LP | 127,500 | 3,339,231 | 127,500 | 3,339,231 | SCHEDULE 13G/A, 2026-08-14 |
| Susquehanna Fundamental Investments, LLC | 15,042 | 3,339,231 | 15,042 | 3,339,231 | SCHEDULE 13G/A, 2026-08-14 |
| Susquehanna Portfolio Strategies, LLC | 121,869 | 3,339,231 | 121,869 | 3,339,231 | SCHEDULE 13G/A, 2026-08-14 |
| Susquehanna Securities, LLC | 3,074,597 | 3,339,231 | 3,074,597 | 3,339,231 | SCHEDULE 13G/A, 2026-08-14 |
| Aberdeen Group plc | 0 | 2,848,117 | 0 | 2,848,117 | SCHEDULE 13G/A, 2026-07-20 |
| abrdn Inc. | 0 | 2,848,117 | 0 | 2,848,117 | SCHEDULE 13G/A, 2026-07-20 |
The latest filing identifies uniQure N.V. by CUSIP N90064101 and gives its principal executive office as Paasheuvelweg 25a, 1105 BP Amsterdam, The Netherlands (SCHEDULE 13G/A, 2026-10-16).
Timeline
| Filed | Holder | Percent | Filing |
|---|---|---|---|
| 2025-07-31 | Aberdeen Group plc | 5.02% | SCHEDULE 13G |
| 2025-08-14 | Avoro Capital Advisors LLC | 6.6% | SCHEDULE 13G |
| 2025-08-14 | Vestal Point Capital, LP | 6.8% | SCHEDULE 13G/A |
| 2025-08-14 | Nantahala Capital Management, LLC | 3.75% | SCHEDULE 13G/A |
| 2025-08-14 | RTW Investments, LP | 9.4% | SCHEDULE 13G/A |
| 2025-10-14 | Aberdeen Group plc | 4.77% | SCHEDULE 13G/A |
| 2025-11-05 | Fmr LLC | 9.8% | SCHEDULE 13G |
| 2025-11-14 | Vestal Point Capital, LP | 0.4% | SCHEDULE 13G/A |
| 2025-11-14 | RTW Investments, LP | 7.2% | SCHEDULE 13G/A |
| 2026-01-29 | Aberdeen Group plc | 5.91% | SCHEDULE 13G/A |
| 2026-02-09 | State Street Corporation | 5.2% | SCHEDULE 13G |
| 2026-02-13 | G1 Execution Services, LLC | 5.7% | SCHEDULE 13G |
| 2026-02-17 | Avoro Capital Advisors LLC | 9.87% | SCHEDULE 13G/A |
| 2026-02-17 | EcoR1 Capital, LLC | 0% | SCHEDULE 13G/A |
| 2026-02-17 | RTW Investments, LP | 6% | SCHEDULE 13G/A |
| 2026-04-30 | Aberdeen Group plc | 8.49% | SCHEDULE 13G/A |
| 2026-05-06 | Fmr LLC | 2.8% | SCHEDULE 13G/A |
| 2026-05-12 | State Street Corporation | 3.6% | SCHEDULE 13G |
| 2026-05-15 | RTW Investments, LP | 4.1% | SCHEDULE 13G/A |
| 2026-07-16 | Jpmorgan Chase & Co | 7% | SCHEDULE 13G |
| 2026-07-20 | Aberdeen Group plc | 4.52% | SCHEDULE 13G/A |
| 2026-08-14 | G1 Execution Services, LLC | 4.8% | SCHEDULE 13G/A |
| 2026-08-14 | RTW Investments, LP | 5.7% | SCHEDULE 13G |
| 2026-10-16 | Jpmorgan Chase & Co. | 8.5% | SCHEDULE 13G/A |
Questions about who owns uniQure N.V.
Who owns uniQure N.V.?
On this page, 3 holders' latest ownership filings report 5% or more of uniQure N.V.: Avoro Capital Advisors LLC (9.87%, Schedule 13G/A, filed 2026-02-17), Jpmorgan Chase & Co. (8.5%, Schedule 13G/A, filed 2026-10-16) and RTW Investments, LP (5.7%, Schedule 13G, filed 2026-08-14).
Who are the largest shareholders of uniQure N.V.?
By the share each holder's latest filing reports, the largest holders of uniQure N.V. on this page are Avoro Capital Advisors LLC (9.87%), Jpmorgan Chase & Co. (8.5%) and RTW Investments, LP (5.7%).
When did Avoro Capital Advisors LLC buy into uniQure N.V.?
The filings give report dates, not purchase dates. The earliest filing from Avoro Capital Advisors LLC on this page is the Schedule 13G, filed 2025-08-14, reporting 6.6%; its latest, Schedule 13G/A filed 2026-02-17, reports 9.87%.
Is this an audit or a full list?
Neither. The ownership list on this page covers only Schedule 13D and 13G filings, which holders make once they own 5% or more of a class of shares (an amendment can report a stake that has since fallen below 5%); 24 such filings are shown here. It is not an audit and not a full cap table: holders who never reached 5% are not listed, and a stake can change after its latest filing.
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Where this comes from
Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.
Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.