MentionFox lists 692 Biotech companies. Of them, 211 are Y Combinator companies (the newest batch here is Fall 2026, with 3); 436 filed a Form D notice with the SEC; 45 won an SBIR or STTR award.
Companies692
Y Combinator211
Form D filers436
SBIR/STTR winners45
By year
- 2026: 467 companies (26 Y Combinator, 425 Form D filers, 16 SBIR/STTR winners); median amount sold $3M across 261 Form D notices
- 2025: 44 companies (13 Y Combinator, 2 Form D filers, 29 SBIR/STTR winners)
- 2024: 17 companies (17 Y Combinator)
- 2022: 28 companies (22 Y Combinator, 6 Form D filers); median amount sold $7.4M across 6 Form D notices
- 2021: 39 companies (38 Y Combinator, 1 Form D filer)
- 2020: 25 companies (25 Y Combinator)
Biotech startups from other years
Companies from before 2020, or from a year with fewer than 15 of them. Every other year has its own full list, linked above.
| Company | What it does | Date | Amount | Round / stage | Record |
|---|---|---|---|---|---|
| Gleam | Automating Data Entry for Clinical Trials | Summer 2023 | Y Combinator batch | Y Combinator listing | |
| Nanograb | Deliver genes to any cell with AI | Summer 2023 | Y Combinator batch | Y Combinator listing | |
| Numen | Engineering a future without cancer deaths. | Summer 2023 | Y Combinator batch | Y Combinator listing | |
| Ohmic Biosciences | Genetically engineering plants for disease resistance. | Summer 2023 | Y Combinator batch | Y Combinator listing | |
| Olio Labs | Combination therapeutics for the world's toughest diseases | Summer 2023 | Y Combinator batch | Y Combinator listing | |
| Adventris Pharmaceuticals | Adventris makes cancer vaccines | Winter 2023 | Y Combinator batch | Y Combinator listing | |
| Diffuse Bio | Generative AI for protein design | Winter 2023 | Y Combinator batch | Y Combinator listing | |
| Invitris | Creating new protein-based drugs at scale | Winter 2023 | Y Combinator batch | Y Combinator listing | |
| Miracle | Accelerate clinical trials with real-time, actionable insights | Winter 2023 | Y Combinator batch | Y Combinator listing | |
| Modulari-T | We teach your immune system to attack and cure cancer | Winter 2023 | Y Combinator batch | Y Combinator listing | |
| Pando Bioscience | Gen-AI Designed Enzymes for Pharmaceutical Innovation | Winter 2023 | Y Combinator batch | Y Combinator listing | |
| Persist AI | Developing long-lasting drug formulations 50% faster | Winter 2023 | Y Combinator batch | Y Combinator listing | |
| AcuraStem Inc (funding history) | Filed Jun 19, 2019 | SEC Form D | |||
| Arpeggio Bio | Arpeggio Bio develops drugs targeting transcription factors using AI… | Summer 2019 | Y Combinator batch | Y Combinator listing | |
| Asher Bio | We build better immunotherapies | Summer 2019 | Y Combinator batch | Y Combinator listing | |
| GEn1E Lifesciences | AI platform accelerating therapies for rare & inflammatory diseases. | Summer 2019 | Y Combinator batch | Y Combinator listing | |
| Kern Systems | Using DNA to store data. | Summer 2019 | Y Combinator batch | Y Combinator listing | |
| Sequence Bio | Discovering the true signals of disease to power life-changing drugs. | Summer 2019 | Y Combinator batch | Y Combinator listing | |
| Shiru | Shiru leverages ML to create proteins to feed the world sustainably | Summer 2019 | Y Combinator batch | Y Combinator listing | |
| 1910 | Multimodal AI Platform for Modality Agnostic Drug Discovery™ | Winter 2019 | Y Combinator batch | Y Combinator listing | |
| Atomic Alchemy | We produce cancer-curing materials used in nuclear medicine. | Winter 2019 | Y Combinator batch | Y Combinator listing | |
| Intact Therapeutics | Smart gels for local drug delivery to the gut | Winter 2019 | Y Combinator batch | Y Combinator listing | |
| Leah Labs | Living therapies for pets first, and their people next | Winter 2019 | Y Combinator batch | Y Combinator listing | |
| Volta Labs, Inc. | Unlocking the utility of genomics for the world. | Winter 2019 | Y Combinator batch | Y Combinator listing | |
| XGenomes | XGenomes is building the sequencing technology of the future | Winter 2019 | Y Combinator batch | Y Combinator listing | |
| YourChoice Therapeutics | YourChoice therapeutics is revolutionizing the contraceptive market… | Winter 2019 | Y Combinator batch | Y Combinator listing | |
| Akelos, Inc. (funding history) | Filed Nov 28, 2018 | $295,000 | SEC Form D | ||
| 64x Bio | Enabling next generation medicines | Summer 2018 | Y Combinator batch | Y Combinator listing | |
| C16 Biosciences | Next-gen ingredients to decarbonize consumer products, starting w/… | Summer 2018 | Y Combinator batch | Y Combinator listing | |
| CB Therapeutics | Fermentation-derived natural products to solve health problems | Summer 2018 | Y Combinator batch | Y Combinator listing | |
| Circumvent | Utilizing monogenic disorders to inform and solve highly complex… | Summer 2018 | Y Combinator batch | Y Combinator listing | |
| Clear Gene | Our tests help eradicate cancer by telling doctors whether they got… | Summer 2018 | Y Combinator batch | Y Combinator listing | |
| Coral Genomics | New clinical tests for managing autoimmune treatments. | Summer 2018 | Y Combinator batch | Y Combinator listing | |
| Data Driven Bioscience | Cancer Diagnosis 10X faster, 10X cheaper | Summer 2018 | Y Combinator batch | Y Combinator listing | |
| Dorian Therapeutics | New therapeutics to rejuvenate tissue and treat age-related diseases | Summer 2018 | Y Combinator batch | Y Combinator listing | |
| HappiLabs | Virtual Lab Managers for scientists and biotech, research Labs | Summer 2018 | Y Combinator batch | Y Combinator listing | |
| Hepatx | Replacing organ transplant with an infusion | Summer 2018 | Y Combinator batch | Y Combinator listing | |
| Mark Cuban Cost Plus Drug Company, PBC | Making low cost versions of high cost generic drugs. | Summer 2018 | Y Combinator batch | Y Combinator listing | |
| Rejuvenation Technologies Inc. | mRNA therapeutics to extend healthspan entering clinical trials | Summer 2018 | Y Combinator batch | Y Combinator listing | |
| Synkrino Biotherapeutics | Synkrino's AI, SATIS is a powerful, unbiased discovery system for… | Summer 2018 | Y Combinator batch | Y Combinator listing | |
| Avro Life Science | Skin patches for generic drug delivery | Winter 2018 | Y Combinator batch | Y Combinator listing | |
| Culture Biosciences | We grow cells for biotech companies. | Winter 2018 | Y Combinator batch | Y Combinator listing | |
| FidoCure® | FidoCure® is the leader in Precision Medicine for Canine Oncology. | Winter 2018 | Y Combinator batch | Y Combinator listing | |
| Lucy Goods, Inc | Lucy’s mission is to reduce tobacco-related harm to zero | Winter 2018 | Y Combinator batch | Y Combinator listing | |
| Macromoltek | Computational antibody design | Winter 2018 | Y Combinator batch | Y Combinator listing | |
| Nectome | Human whole body end-of-life preservation for later revival. | Winter 2018 | Y Combinator batch | Y Combinator listing | |
| Persephone Biosciences | We are using the gut microbiome to end cancer | Winter 2018 | Y Combinator batch | Y Combinator listing | |
| Sixfold Bioscience | Delivering RNA therapies. | Winter 2018 | Y Combinator batch | Y Combinator listing | |
| Tradewind BioScience | Tradewind translates scientific insight into innovative ways of… | Winter 2018 | Y Combinator batch | Y Combinator listing | |
| ZBiotics | ZBiotics makes genetically engineered probiotics. | Winter 2018 | Y Combinator batch | Y Combinator listing | |
| Entocycle | Automated factory to produce insect protein for farm animals | Summer 2017 | Y Combinator batch | Y Combinator listing | |
| Nobell Foods | Cheese and dairy products from plant-derived dairy proteins | Summer 2017 | Y Combinator batch | Y Combinator listing | |
| Oncobox | Finding the right cancer drug for each patient | Summer 2017 | Y Combinator batch | Y Combinator listing | |
| Rev Genomics | Rev is a biotechnology company creating better plants. | Summer 2017 | Y Combinator batch | Y Combinator listing | |
| Delee | Blood testing device for early diagnosis of cancer and treatment… | Winter 2017 | Y Combinator batch | Y Combinator listing | |
| Helix Nanotechnologies | Next-generation mRNA platform to solve cancer, COVID and climate. | Winter 2017 | Y Combinator batch | Y Combinator listing | |
| Indee Labs | Enabling T cell immunotherapy discovery, development and manufacturing | Winter 2017 | Y Combinator batch | Y Combinator listing | |
| Sigma Genetics | Sigma Genetics is a biotechnology company that is building… | Winter 2017 | Y Combinator batch | Y Combinator listing | |
| Solugen | Decarbonizing the chemicals industry. | Winter 2017 | Y Combinator batch | Y Combinator listing | |
| Synvivia | Synvivia applies chemical control over cell behavior | Summer 2016 | Y Combinator batch | Y Combinator listing | |
| HistoWiz | Accelerating Histopathology for Cancer Research | Winter 2016 | Y Combinator batch | Y Combinator listing | |
| Loop Genomics | Novel long-read DNA sequencing technology | Winter 2016 | Y Combinator batch | Y Combinator listing | |
| Luminist Labs | Diagnostic platform for early detection of liver disease | Winter 2016 | Y Combinator batch | Y Combinator listing | |
| Lygos | Lygos (W16) built and commercialized sustainable, high-performance… | Winter 2016 | Y Combinator batch | Y Combinator listing | |
| Opentrons | We make robots for biologists | Winter 2016 | Y Combinator batch | Y Combinator listing | |
| Qvin | Empowering women | Winter 2016 | Y Combinator batch | Y Combinator listing | |
| Numerion Labs | Artificial intelligence for drug discovery. | Winter 2015 | Y Combinator batch | Y Combinator listing | |
| Shasqi | Targeting Cancer with Click Chemistry | Winter 2015 | Y Combinator batch | Y Combinator listing | |
| X-Zell | Early, pain-free cancer detection | Winter 2015 | Y Combinator batch | Y Combinator listing | |
| One Codex | Data platform for metagenomics and the microbiome. | Summer 2014 | Y Combinator batch | Y Combinator listing | |
| Benchling | Unlocking the power of biotech with modern software for modern science | Summer 2012 | Y Combinator batch | Y Combinator listing | |
| Science Exchange | Powering scientific outsourcing | Summer 2011 | Y Combinator batch | Y Combinator listing |
Selling to these companies?
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Healthcare and health tech (103 shared) AI (88 shared) Drug discovery (45 shared) Medical device and diagnostics (33 shared) Climate tech (14 shared) Manufacturing and industrial (11 shared)
Figures come only from the record linked in each row; a blank means the record gives none. How these lists are built.