As of November 10, 2026, 4 holders' latest Schedule 13D or 13G filings report owning 5% or more of Zai Lab Limited. The largest reported stake is RTW Investments, LP's, at 6.3%. 14 filings are on record since August 6, 2025 (Schedule 13G, February 17, 2026).
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Key facts
- · Reporting person: TCG Crossover GP II, LLC · Sole voting: 0 · Shared voting: 29,565,330 · Sole dispositive: 0 · Shared dispositive: 29,565,330 · SCHEDULE 13G, 2026-06-11
- · Holder: RA Capital Management, L.P. · Percent: 5.2% · SCHEDULE 13G
- · Holder: RTW Investments, LP · Percent: 6.3% · SCHEDULE 13G
- · Holder: Capital World Investors · Percent: 0.2% · SCHEDULE 13G/A
- · Holder: Qiming Corporate GP IV, Ltd. · Percent: 4.4% · SCHEDULE 13G/A
Zai Lab Limited has 14 Schedule 13D or 13G filings on record since 2025-08-06. 4 holders' latest filing reports 5% or more of ordinary shares, par value $0.000006 per share. Each figure below is the holder's own, as filed, with the filing linked.
Holders
| Holder | Percent | Shares | Latest | Event date |
|---|---|---|---|---|
| RTW Investments, LP | 6.3% | 69,590,320 | SCHEDULE 13G, 2026-02-17 | 2025-12-31 |
| Qiming Corporate GP IV, Ltd. | 5.97% | 66,329,320 | SCHEDULE 13G/A, 2025-08-12 | 2025-06-30 |
| 5.3% | 59,130,750 | SCHEDULE 13G, 2026-06-11 | 2026-06-02 | |
| RA Capital Management, L.P. | 5.2% | 57,435,330 | SCHEDULE 13G, 2026-04-06 | 2026-03-30 |
| Qiming Corporate GP IV, Ltd. | 4.4% | 48,883,643 | SCHEDULE 13G/A, 2026-02-13 | 2025-12-31 |
| Wellington Management Group LLP | 4.3% | 48,112,590 | SCHEDULE 13G/A, 2026-02-10 | 2025-12-31 |
| Fmr LLC | 3.9% | 43,535,993 | SCHEDULE 13G/A, 2026-02-05 | 2025-12-31 |
| Capital World Investors | 0.2% | 1,723,600 | SCHEDULE 13G/A, 2026-02-13 | 2025-12-31 |
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Keep reading
More on Zai Lab Limited and the records around it.
Zai Lab Limited elsewhere on the record
Companies that share a holder
- TCG Crossover GP II, LLC also filed stake reports on 21 other companies: ALX Oncology Holdings Inc. (Aug 2026), First Tracks Biotherapeutics, Inc. (Aug 2026), Fulcrum Therapeutics, Inc. (Aug 2026)
- RTW Investments, LP also filed stake reports on 43 other companies: CG Oncology, Inc. (Aug 2026), iRhythm Holdings, Inc. (Aug 2026), Kailera Therapeutics, Inc. (Aug 2026)
- RA Capital Management, L.P. also filed stake reports on 100 other companies: Climb Bio, Inc. (Nov 2026), Bambusa Therapeutics, Inc. (Nov 2026), SOLID BIOSCIENCES INC. (Nov 2026)
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Voting and dispositive power, as filed
| Reporting person | Sole voting | Shared voting | Sole dispositive | Shared dispositive | Filing |
|---|---|---|---|---|---|
| TCG Crossover GP II, LLC | 0 | 29,565,330 | 0 | 29,565,330 | SCHEDULE 13G, 2026-06-11 |
| TCG Crossover Fund II, L.P. | 0 | 29,565,330 | 0 | 29,565,330 | SCHEDULE 13G, 2026-06-11 |
| TCG Crossover GP III, LLC | 0 | 29,565,420 | 0 | 29,565,420 | SCHEDULE 13G, 2026-06-11 |
| TCG Crossover Fund III, L.P. | 0 | 29,565,420 | 0 | 29,565,420 | SCHEDULE 13G, 2026-06-11 |
| Chen Yu | 0 | 59,130,750 | 0 | 59,130,750 | SCHEDULE 13G, 2026-06-11 |
The latest filing identifies Zai Lab Limited by CUSIP 98887Q104 and gives its principal executive office as 314 Main Street, 4th Floor, Suite 100, Cambridge, MA 02142 (SCHEDULE 13G, 2026-06-11).
Timeline
| Filed | Holder | Percent | Filing |
|---|---|---|---|
| 2025-08-06 | Fmr LLC | 8.5% | SCHEDULE 13G/A |
| 2025-08-12 | Wellington Management Group LLP | 4.5% | SCHEDULE 13G/A |
| 2025-08-12 | Qiming Corporate GP IV, Ltd. | 5.97% | SCHEDULE 13G/A |
| 2025-08-14 | RTW Investments, LP | 5.1% | SCHEDULE 13G |
| 2025-11-05 | Fmr LLC | 6.4% | SCHEDULE 13G/A |
| 2025-11-12 | Wellington Management Group LLP | 6% | SCHEDULE 13G |
| 2025-11-14 | RTW Investments, LP | 2.1% | SCHEDULE 13G/A |
| 2026-02-05 | Fmr LLC | 3.9% | SCHEDULE 13G/A |
| 2026-02-10 | Wellington Management Group LLP | 4.3% | SCHEDULE 13G/A |
| 2026-02-13 | Capital World Investors | 0.2% | SCHEDULE 13G/A |
| 2026-02-13 | Qiming Corporate GP IV, Ltd. | 4.4% | SCHEDULE 13G/A |
| 2026-02-17 | RTW Investments, LP | 6.3% | SCHEDULE 13G |
| 2026-04-06 | RA Capital Management, L.P. | 5.2% | SCHEDULE 13G |
| 2026-06-11 | Chen Yu | 5.3% | SCHEDULE 13G |
Questions about who owns Zai Lab Limited
Who owns Zai Lab Limited?
On this page, 4 holders' latest ownership filings report 5% or more of Zai Lab Limited: RTW Investments, LP (6.3%, Schedule 13G, filed 2026-02-17), Qiming Corporate GP IV, Ltd. (5.97%, Schedule 13G/A, filed 2025-08-12), Chen Yu (5.3%, Schedule 13G, filed 2026-06-11) and RA Capital Management, L.P. (5.2%, Schedule 13G, filed 2026-04-06).
Who are the largest shareholders of Zai Lab Limited?
By the share each holder's latest filing reports, the largest holders of Zai Lab Limited on this page are RTW Investments, LP (6.3%), Qiming Corporate GP IV, Ltd. (5.97%) and Chen Yu (5.3%).
When did RTW Investments, LP buy into Zai Lab Limited?
The filings give report dates, not purchase dates. The earliest filing from RTW Investments, LP on this page is the Schedule 13G, filed 2025-08-14, reporting 5.1%; its latest, Schedule 13G filed 2026-02-17, reports 6.3%.
Is this an audit or a full list?
Neither. The ownership list on this page covers only Schedule 13D and 13G filings, which holders make once they own 5% or more of a class of shares (an amendment can report a stake that has since fallen below 5%); 14 such filings are shown here. It is not an audit and not a full cap table: holders who never reached 5% are not listed, and a stake can change after its latest filing.
Also on the record for Zai Lab Limited
| Date | Record | Figure | Our page | Source |
|---|---|---|---|---|
| November 9, 2026 | Form D, private offering | $249.93M sold | Form D page | Source |
| May 21, 2026 | Leadership change filing (Form 8-K, Item 5.02) | — | Leadership changes | Source |
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Where this comes from
Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.
Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.