As of November 7, 2026, 4 holders' latest Schedule 13D or 13G filings report owning 5% or more of Sol-Gel Technologies Ltd. The largest reported stake is Moshe Arkin's, at 56.6%. 11 filings are on record since August 29, 2025 (Schedule 13D/A, April 15, 2026).
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Key facts
- · Reporting person: Opaleye Management Inc. · Sole voting: 0 · Shared voting: 540,000 · Sole dispositive: 0 · Shared dispositive: 540,000 · SCHEDULE 13G/A, 2026-11-06
- · Reporting person: Trails Edge Capital Partners, LP · Sole voting: 166,473 · Shared voting: 0 · Sole dispositive: 166,473 · Shared dispositive: 0 · SCHEDULE 13G, 2026-10-27
- · Reporting person: Phoenix Financial Ltd. · Sole voting: 0 · Shared voting: 161,826 · Sole dispositive: 0 · Shared dispositive: 161,826 · SCHEDULE 13G/A, 2026-06-09
- · Holder: Opaleye Management Inc. · Percent: 15.41% · SCHEDULE 13G/A
- · Reporting person: Moshe Arkin · Sole voting: 143,257 · Shared voting: 1,806,856 · Sole dispositive: 143,257 · Shared dispositive: 1,806,856 · SCHEDULE 13D/A, 2026-04-15
Sol-Gel Technologies Ltd has 11 Schedule 13D or 13G filings on record since 2025-08-29. 4 holders' latest filing reports 5% or more of ordinary shares, par value nis 1.00 per share.. Each figure below is the holder's own, as filed, with the filing linked.
Holders
| Holder | Percent | Shares | Latest | Event date |
|---|---|---|---|---|
| 56.6% | 1,950,113 | SCHEDULE 13D/A, 2026-04-15 | 2026-03-25 | |
| Opaleye Management Inc. | 16.49% | 540,000 | SCHEDULE 13G/A, 2026-11-06 | 2026-09-30 |
| Great Point Partners, LLC | 8.45% | 274,363 | SCHEDULE 13G, 2026-03-31 | 2026-03-24 |
| Trails Edge Capital Partners, LP | 5.1% | 166,473 | SCHEDULE 13G, 2026-10-27 | 2026-10-20 |
| Phoenix Financial Ltd. | 4.99% | 161,826 | SCHEDULE 13G/A, 2026-06-09 | 2026-06-02 |
| 4.4% | 122,755 | SCHEDULE 13G, 2025-11-13 | 2025-09-30 |
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More on Sol-Gel Technologies Ltd and the records around it.
Sol-Gel Technologies Ltd elsewhere on the record
Companies that share a holder
- Moshe Arkin also filed stake reports on 1 other company: Odysight.ai Inc. (Sep 2026)
- Migdal Insurance & Financial Holdings Ltd also filed stake reports on 10 other companies: Camtek Ltd (Oct 2026), Enlight Renewable Energy Ltd (Jul 2026), Ormat Technologies, Inc. (Jul 2026)
- Opaleye Management Inc. also filed stake reports on 12 other companies: Codexis, Inc. (Nov 2026), Gossamer Bio, Inc. (Nov 2026), Pasithea Therapeutics Corp. (Nov 2026)
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Voting and dispositive power, as filed
| Reporting person | Sole voting | Shared voting | Sole dispositive | Shared dispositive | Filing |
|---|---|---|---|---|---|
| Moshe Arkin | 143,257 | 1,806,856 | 143,257 | 1,806,856 | SCHEDULE 13D/A, 2026-04-15 |
| M. Arkin Dermatology Ltd. | — | 1,806,856 | — | 1,806,856 | SCHEDULE 13D/A, 2026-04-15 |
| Opaleye Management Inc. | 0 | 540,000 | 0 | 540,000 | SCHEDULE 13G/A, 2026-11-06 |
| Opaleye, L.P. | 0 | 525,000 | 0 | 525,000 | SCHEDULE 13G/A, 2026-11-06 |
| James Silverman | 0 | 540,000 | 0 | 540,000 | SCHEDULE 13G/A, 2026-11-06 |
| Trails Edge Capital Partners, LP | 166,473 | 0 | 166,473 | 0 | SCHEDULE 13G, 2026-10-27 |
| Trails Edge Biotechnology Master Fund, LP | 166,473 | 0 | 166,473 | 0 | SCHEDULE 13G, 2026-10-27 |
| Ortav Yehudai | 166,473 | 0 | 166,473 | 0 | SCHEDULE 13G, 2026-10-27 |
| Phoenix Financial Ltd. | 0 | 161,826 | 0 | 161,826 | SCHEDULE 13G/A, 2026-06-09 |
The latest filing identifies Sol-Gel Technologies Ltd by CUSIP M8694L137 and gives its principal executive office as 6 HaChoshlim St., Bldg. C, Herzliya (SCHEDULE 13G/A, 2026-11-06).
Source of funds (Item 3)
This amendment to Schedule 13D is being filed solely to update the percentage holdings of the Reporting Persons following the closing of the Issuer's underwritten offering that closed on March 25, 2026.Moshe Arkin, SCHEDULE 13D/A, 2026-04-15
Timeline
| Filed | Holder | Percent | Filing |
|---|---|---|---|
| 2025-08-29 | Opaleye Management Inc. | 5% | SCHEDULE 13G |
| 2025-11-13 | Migdal Sal Domestic Equities | 4.4% | SCHEDULE 13G |
| 2025-11-14 | Opaleye Management Inc. | 7.35% | SCHEDULE 13G/A |
| 2025-11-17 | Opaleye Management Inc. | 13.19% | SCHEDULE 13G/A |
| 2026-03-23 | Opaleye Management Inc. | 16.52% | SCHEDULE 13G/A |
| 2026-03-31 | Great Point Partners, LLC | 8.45% | SCHEDULE 13G |
| 2026-04-15 | Moshe Arkin | 56.6% | SCHEDULE 13D/A |
| 2026-05-06 | Opaleye Management Inc. | 15.41% | SCHEDULE 13G/A |
| 2026-06-09 | Phoenix Financial Ltd. | 4.99% | SCHEDULE 13G/A |
| 2026-10-27 | Trails Edge Capital Partners, LP | 5.1% | SCHEDULE 13G |
| 2026-11-06 | Opaleye Management Inc. | 16.49% | SCHEDULE 13G/A |
Questions about who owns Sol-Gel Technologies Ltd
Who owns Sol-Gel Technologies Ltd?
On this page, 4 holders' latest ownership filings report 5% or more of Sol-Gel Technologies Ltd: Moshe Arkin (56.6%, Schedule 13D/A, filed 2026-04-15), Opaleye Management Inc. (16.49%, Schedule 13G/A, filed 2026-11-06), Great Point Partners, LLC (8.45%, Schedule 13G, filed 2026-03-31) and Trails Edge Capital Partners, LP (5.1%, Schedule 13G, filed 2026-10-27).
Who are the largest shareholders of Sol-Gel Technologies Ltd?
By the share each holder's latest filing reports, the largest holders of Sol-Gel Technologies Ltd on this page are Moshe Arkin (56.6%), Opaleye Management Inc. (16.49%) and Great Point Partners, LLC (8.45%).
When did Moshe Arkin buy into Sol-Gel Technologies Ltd?
The filings give report dates, not purchase dates. The earliest filing from Moshe Arkin on this page is the Schedule 13D/A, filed 2026-04-15, reporting 56.6%. That earliest filing is itself an amendment, which updates an earlier report.
Is this an audit or a full list?
Neither. The ownership list on this page covers only Schedule 13D and 13G filings, which holders make once they own 5% or more of a class of shares (an amendment can report a stake that has since fallen below 5%); 11 such filings are shown here. It is not an audit and not a full cap table: holders who never reached 5% are not listed, and a stake can change after its latest filing.
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Where this comes from
Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.
Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.