Lexeo Therapeutics, Inc. has 31 Schedule 13D or 13G filings on record since 2025-08-07. 11 holders' latest filing reports 5% or more of common stock. Each figure below is the holder's own, as filed, with the filing linked.
Holders
| Holder | Percent | Shares | Latest | Event date |
|---|---|---|---|---|
| Balyasny Asset Management L.P. | 9.99% | 7,844,311 | SCHEDULE 13G/A, 2026-08-14 | 2026-06-30 |
| Janus Henderson Group Plc | 9.99% | 7,291,434 | SCHEDULE 13G/A, 2025-12-08 | 2025-11-28 |
| Affinity Asset Advisors, LLC | 8.4% | 6,674,913 | SCHEDULE 13G/A, 2026-08-13 | 2026-06-30 |
| Suvretta Capital Management, LLC | 7.7% | 5,674,778 | SCHEDULE 13G, 2026-04-13 | 2026-04-06 |
| Vestal Point Capital, LP | 7.5% | 4,117,302 | SCHEDULE 13G/A, 2025-11-14 | 2025-09-30 |
| Kenneth Griffin | 7.4% | 5,498,219 | SCHEDULE 13G/A, 2026-02-17 | 2025-12-31 |
| RA Capital Management, L.P. | 6.9% | 5,000,000 | SCHEDULE 13G, 2025-10-27 | 2025-10-20 |
| BlackRock, Inc. | 6.7% | 4,885,814 | SCHEDULE 13G, 2026-01-21 | 2025-12-31 |
| State Street Corporation | 5.5% | 4,354,775 | SCHEDULE 13G, 2026-08-07 | 2026-06-30 |
| Paradigm BioCapital Advisors LP | 5.3% | 4,175,382 | SCHEDULE 13G/A, 2026-08-14 | 2026-06-30 |
| Frazier Life Sciences Public Fund, L.P. | 5.1% | 3,698,271 | SCHEDULE 13G/A, 2026-02-13 | 2025-12-31 |
| OrbiMed Advisors LLC | 4.1% | 3,203,050 | SCHEDULE 13G, 2026-08-14 | 2026-06-30 |
| Longitude Capital Partners IV, LLC | 3.8% | 2,765,381 | SCHEDULE 13G/A, 2025-11-14 | 2025-09-30 |
| Millennium Management LLC | 3.2% | 2,313,642 | SCHEDULE 13G/A, 2025-11-07 | 2025-09-30 |
| The Vanguard Group | 0% | 0 | SCHEDULE 13G/A, 2026-03-27 | 2026-03-13 |
Timeline
| Filed | Holder | Percent | Filing |
|---|---|---|---|
| 2025-08-07 | Millennium Management LLC | 5.3% | SCHEDULE 13G/A |
| 2025-08-14 | Vestal Point Capital, LP | 6% | SCHEDULE 13G |
| 2025-08-14 | Citadel Advisors LLC | 9.6% | SCHEDULE 13G/A |
| 2025-08-14 | Balyasny Asset Management L.P. | 9.99% | SCHEDULE 13G |
| 2025-08-14 | Janus Henderson Group Plc | 11.1% | SCHEDULE 13G/A |
| 2025-08-14 | Frazier Life Sciences Public Fund, L.P. | 5.7% | SCHEDULE 13G/A |
| 2025-10-17 | BlackRock, Inc. | 4% | SCHEDULE 13G/A |
| 2025-10-27 | RA Capital Management, L.P. | 6.9% | SCHEDULE 13G |
| 2025-11-07 | Millennium Management LLC | 3.2% | SCHEDULE 13G/A |
| 2025-11-14 | Vestal Point Capital, LP | 7.5% | SCHEDULE 13G/A |
| 2025-11-14 | Balyasny Asset Management L.P. | 9.99% | SCHEDULE 13G/A |
| 2025-11-14 | Longitude Capital Partners IV, LLC | 3.8% | SCHEDULE 13G/A |
| 2025-11-14 | Janus Henderson Group Plc | 11.3% | SCHEDULE 13G/A |
| 2025-11-20 | Paradigm BioCapital Advisors LP | 5% | SCHEDULE 13G |
| 2025-12-08 | Janus Henderson Group Plc | 9.99% | SCHEDULE 13G/A |
| 2026-01-21 | BlackRock, Inc. | 6.7% | SCHEDULE 13G |
| 2026-01-29 | Affinity Asset Advisors, LLC | 7.1% | SCHEDULE 13G/A |
| 2026-01-30 | The Vanguard Group | 5.33% | SCHEDULE 13G |
| 2026-02-13 | Frazier Life Sciences Public Fund, L.P. | 5.1% | SCHEDULE 13G/A |
| 2026-02-17 | Paradigm BioCapital Advisors LP | 6.5% | SCHEDULE 13G/A |
| 2026-02-17 | Kenneth Griffin | 7.4% | SCHEDULE 13G/A |
| 2026-02-17 | Balyasny Asset Management L.P. | 9.89% | SCHEDULE 13G/A |
| 2026-03-27 | The Vanguard Group | 0% | SCHEDULE 13G/A |
| 2026-04-13 | Suvretta Capital Management, LLC | 7.7% | SCHEDULE 13G |
| 2026-05-15 | Paradigm BioCapital Advisors LP | 8.3% | SCHEDULE 13G/A |
| 2026-05-15 | Balyasny Asset Management L.P. | 9.69% | SCHEDULE 13G/A |
| 2026-08-07 | State Street Corporation | 5.5% | SCHEDULE 13G |
| 2026-08-13 | Affinity Asset Advisors, LLC | 8.4% | SCHEDULE 13G/A |
| 2026-08-14 | OrbiMed Advisors LLC | 4.1% | SCHEDULE 13G |
| 2026-08-14 | Paradigm BioCapital Advisors LP | 5.3% | SCHEDULE 13G/A |
| 2026-08-14 | Balyasny Asset Management L.P. | 9.99% | SCHEDULE 13G/A |
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Where this comes from
Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.
Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.