Tyra Biosciences, Inc. has 20 Schedule 13D or 13G filings on record since 2025-08-14. 8 holders' latest filing reports 5% or more of common stock, $0.0001 par value per share. Each figure below is the holder's own, as filed, with the filing linked.
Holders
| Holder | Percent | Shares | Latest | Event date |
|---|---|---|---|---|
| RA Capital Management, L.P. | 19.9% | 14,130,492 | SCHEDULE 13D/A, 2026-09-17 | 2026-09-15 |
| Fmr LLC | 14.4% | 7,747,648 | SCHEDULE 13G, 2026-04-07 | 2026-03-31 |
| Janus Henderson Group Plc | 7.2% | 3,890,589 | SCHEDULE 13G/A, 2026-05-15 | 2026-03-31 |
| Dapice Joshua J. | 6.6% | 3,580,818 | SCHEDULE 13G/A, 2026-05-12 | 2026-03-31 |
| Bvf Partners L P | 6.1% | 4,215,886 | SCHEDULE 13G, 2026-09-21 | 2026-09-14 |
| Nextech VI Oncology SCSp | 6% | 3,553,585 | SCHEDULE 13G/A, 2026-08-14 | 2026-06-30 |
| Paradigm BioCapital Advisors LP | 5.8% | 3,473,453 | SCHEDULE 13G, 2026-09-17 | 2026-09-10 |
| BlackRock, Inc. | 5% | 2,976,228 | SCHEDULE 13G, 2026-07-30 | 2026-06-30 |
| Todd Harris | 4.8% | 2,913,342 | SCHEDULE 13G/A, 2026-05-14 | 2026-03-31 |
| Vestal Point Capital, LP | 4.5% | 2,425,000 | SCHEDULE 13G/A, 2025-11-14 | 2025-09-30 |
| Commodore Capital LP | 4.2% | 2,475,000 | SCHEDULE 13G/A, 2026-05-15 | 2026-03-31 |
| Canaan XI L.P. | 1.4% | 750,000 | SCHEDULE 13G/A, 2026-04-24 | 2026-03-31 |
| Farallon Capital Management, L.L.C. | 0% | 6,000 | SCHEDULE 13G/A, 2026-08-14 | 2026-06-30 |
Timeline
| Filed | Holder | Percent | Filing |
|---|---|---|---|
| 2025-08-14 | Janus Henderson Group Plc | 5.4% | SCHEDULE 13G/A |
| 2025-11-14 | Vestal Point Capital, LP | 4.5% | SCHEDULE 13G/A |
| 2025-11-14 | Commodore Capital LP | 6.3% | SCHEDULE 13G/A |
| 2026-02-13 | Canaan XI L.P. | 5.5% | SCHEDULE 13G/A |
| 2026-02-13 | Todd Harris | 5.1% | SCHEDULE 13G |
| 2026-02-17 | Bvf Partners L P | 4% | SCHEDULE 13G/A |
| 2026-02-20 | Dapice Joshua J. | 5.6% | SCHEDULE 13G |
| 2026-03-06 | RA Capital Management, L.P. | 21.2% | SCHEDULE 13D/A |
| 2026-04-07 | Fmr LLC | 14.4% | SCHEDULE 13G |
| 2026-04-24 | Canaan XI L.P. | 1.4% | SCHEDULE 13G/A |
| 2026-05-12 | Dapice Joshua J. | 6.6% | SCHEDULE 13G/A |
| 2026-05-14 | Todd Harris | 4.8% | SCHEDULE 13G/A |
| 2026-05-15 | Janus Henderson Group Plc | 7.2% | SCHEDULE 13G/A |
| 2026-05-15 | Commodore Capital LP | 4.2% | SCHEDULE 13G/A |
| 2026-07-30 | BlackRock, Inc. | 5% | SCHEDULE 13G |
| 2026-08-14 | Farallon Capital Management, L.L.C. | 0% | SCHEDULE 13G/A |
| 2026-08-14 | Nextech VI Oncology SCSp | 6% | SCHEDULE 13G/A |
| 2026-09-17 | Paradigm BioCapital Advisors LP | 5.8% | SCHEDULE 13G |
| 2026-09-17 | RA Capital Management, L.P. | 19.9% | SCHEDULE 13D/A |
| 2026-09-21 | Bvf Partners L P | 6.1% | SCHEDULE 13G |
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Where this comes from
Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.
Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.