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5%+ stakes · Schedule 13D and 13G

Edgewise Therapeutics, Inc.: 5%+ holders

Who has reported owning 5% or more of Edgewise Therapeutics, Inc., from Schedule 13D and 13G filings: each holder's stake as filed, the timeline, and the purpose each 13D states, quoted.

At 5% or more5
Filings13
Latest filing2026-08-14

Edgewise Therapeutics, Inc. has 13 Schedule 13D or 13G filings on record since 2025-07-17. 5 holders' latest filing reports 5% or more of common stock, par value $0.0001 per share. Each figure below is the holder's own, as filed, with the filing linked.

Holders

HolderPercentSharesLatestEvent date
Paradigm BioCapital Advisors LP9.5%10,215,455SCHEDULE 13G/A, 2026-08-142026-06-30
RA Capital Management, L.P.7.8%8,392,730SCHEDULE 13G/A, 2026-08-142026-06-30
BlackRock, Inc.5.5%5,824,866SCHEDULE 13G/A, 2025-07-172025-06-30
Janus Henderson Group Plc5.5%5,915,556SCHEDULE 13G, 2026-05-152026-03-31
Fmr LLC5.1%5,489,135SCHEDULE 13G, 2026-08-062026-06-30
Novo Holdings A/S4.9%5,350,000SCHEDULE 13D/A, 2026-04-272026-04-23
Perceptive Advisors LLC4.4%4,639,949SCHEDULE 13G/A, 2025-08-142025-06-30
Baker Bros. Advisors LP3.4%3,701,719SCHEDULE 13G/A, 2026-08-142026-06-30

Timeline

FiledHolderPercentFiling
2025-07-17BlackRock, Inc.5.5%SCHEDULE 13G/A
2025-08-14Perceptive Advisors LLC4.4%SCHEDULE 13G/A
2025-08-14Baker Bros. Advisors LP6.9%SCHEDULE 13G/A
2025-08-14Janus Henderson Group Plc5.2%SCHEDULE 13G/A
2025-11-14RA Capital Management, L.P.9.9%SCHEDULE 13G/A
2025-11-14Janus Henderson Group Plc4.7%SCHEDULE 13G/A
2026-02-17Paradigm BioCapital Advisors LP6.2%SCHEDULE 13G/A
2026-04-27Novo Holdings A/S4.9%SCHEDULE 13D/A
2026-05-15Janus Henderson Group Plc5.5%SCHEDULE 13G
2026-08-06Fmr LLC5.1%SCHEDULE 13G
2026-08-14Baker Bros. Advisors LP3.4%SCHEDULE 13G/A
2026-08-14Paradigm BioCapital Advisors LP9.5%SCHEDULE 13G/A
2026-08-14RA Capital Management, L.P.7.8%SCHEDULE 13G/A

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Where this comes from

Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.

Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.

Cite this page

Permanent URL: https://mentionfox.com/stakes/edgewise-therapeutics
Last updated 2026-09-27
Primary record: SEC filing 1 · SEC filing 2 · SEC filing 3 · SEC filing 4
Edgewise Therapeutics, Inc. 5%+ holders: 5 at 5% or more, largest Paradigm BioCapital Advisors LP 9.5%. MentionFox, 2026-09-27. https://mentionfox.com/stakes/edgewise-therapeutics