As of November 10, 2026, Praxis Precision Medicines, Inc. is a publicly traded company (Nasdaq: PRAX); its largest reported holder is Fidelity (FMR), with 9.2% on Schedule 13G/A of November 5, 2026, then Perceptive Advisors (7.2%) (Schedule 13G/A, November 5, 2026).
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Is Praxis Precision Medicines, Inc. a real, registered company?
- Praxis Precision Medicines, Inc. files with the SEC under CIK 1689548 (its SEC filings).
- Its shares are listed under the ticker PRAX on Nasdaq (SEC company record).
- Incorporated in Delaware; business address in Boston, Massachusetts, as its SEC filings state.
- Court and bankruptcy records: see Before you sign or pay below.
Before you sign or pay
- Court and bankruptcy: No federal court case or bankruptcy filing found under PRAXIS PRECISION MEDICINES INC. in our court records and SEC 8-K records (as of 2026-11-10).
- Ownership: 5%+ holders are reported on Schedule 13D or 13G; the latest names Fidelity (FMR) (filed 2026-11-05).
Who are Praxis Precision Medicines, Inc.'s owners and officers?
Praxis Precision Medicines, Inc.: incorporated in Delaware; business address in Boston, Massachusetts; industry Pharmaceutical Preparations (Schedule 13G/A, 2026-11-05).
| Report | Holder | Share |
|---|---|---|
| Schedule 13G/A, 2026-11-05 | Fmr LLC | 9.2% |
| Schedule 13G/A, 2026-08-14 | Orbis Investment Management LTD | 5.5% |
| Schedule 13G/A, 2026-05-15 | Orbis Investment Management LTD | 8.9% |
| Schedule 13G/A, 2026-05-15 | Point72 Biotech Private Investments, LLC | 0.2% |
| Schedule 13G, 2026-05-15 | Baker Bros. Advisors LP | 6.3% |
| Schedule 13G/A, 2026-05-06 | Fmr LLC | 7.7% |
| Schedule 13G, 2026-04-30 | Vanguard Capital Management | 5.09% |
| Schedule 13G/A, 2026-03-27 | The Vanguard Group | 0% |
| Schedule 13G, 2026-02-17 | Orbis Investment Management LTD | 5% |
| Schedule 13G/A, 2026-02-17 | Perceptive Advisors LLC | 7.2% |
| Schedule 13G/A, 2026-02-17 | Steven A. Cohen | 6.1% |
| Schedule 13G/A, 2026-02-12 | Adage Capital Management, L.P. | 3.83% |
Questions about who owns Praxis Precision Medicines, Inc.
Who owns Praxis Precision Medicines, Inc.?
On this page, 6 holders' latest ownership filings report 5% or more of Praxis Precision Medicines, Inc.: Fmr LLC (9.2%, Schedule 13G/A, filed 2026-11-05), Perceptive Advisors LLC (7.2%, Schedule 13G/A, filed 2026-02-17), Baker Bros. Advisors LP (6.3%, Schedule 13G, filed 2026-05-15), Steven A. Cohen (6.1%, Schedule 13G/A, filed 2026-02-17) and Orbis Investment Management LTD (5.5%, Schedule 13G/A, filed 2026-08-14); 1 more is listed above.
Who are the largest shareholders of Praxis Precision Medicines, Inc.?
By the share each holder's latest filing reports, the largest holders of Praxis Precision Medicines, Inc. on this page are Fmr LLC (9.2%), Perceptive Advisors LLC (7.2%) and Baker Bros. Advisors LP (6.3%).
When did Fmr LLC buy into Praxis Precision Medicines, Inc.?
The filings give report dates, not purchase dates. The earliest filing from Fmr LLC on this page is the Schedule 13G/A, filed 2026-05-06, reporting 7.7%; its latest, Schedule 13G/A filed 2026-11-05, reports 9.2%. That earliest filing is itself an amendment, which updates an earlier report.
Is this an audit or a full list?
Neither. The ownership list on this page covers only Schedule 13D and 13G filings, which holders make once they own 5% or more of a class of shares (an amendment can report a stake that has since fallen below 5%); 12 such filings are shown here. It is not an audit and not a full cap table: holders who never reached 5% are not listed, and a stake can change after its latest filing.
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What the Full Report on Praxis Precision Medicines, Inc. covers
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What They Do, And How The Money Works
Who Runs It, And How To Reach Them
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Which insiders own Praxis Precision Medicines, Inc. shares?
Directors, officers and holders of 10% or more report their shares on Forms 3, 4 and 5. Each line is the latest such report, largest holding first.
- , a 10% owner: 4,421,660 shares (15.8% of shares outstanding), held indirectly (the form names the holder only in its footnotes), on a joint filing (Form 4, 2025-10-17).
- , a 10% owner: 4,421,660 shares (15.8% of shares outstanding), held indirectly (the form names the holder only in its footnotes), on a joint filing (Form 4, 2025-10-17).
- Adage Capital, a 10% owner: 4,421,660 shares (15.8% of shares outstanding), held indirectly (the form names the holder only in its footnotes), on a joint filing (Form 4, 2025-10-17).
- , the chief executive and a director: 56,495 shares (0.20% of shares outstanding) (Form 4, 2026-07-08).
- , the chief financial officer: 31,167 shares (0.11% of shares outstanding) (Form 4, 2026-05-19).
Shares outstanding: 27,951,553 as of 2026-11-04, from the company's latest SEC cover page.
How much has Praxis Precision Medicines, Inc. raised?
No fundraising or offering filing from Praxis Precision Medicines, Inc. is on file with us.
Keep reading
More on Praxis Precision Medicines, Inc. and the records around it.
Praxis Precision Medicines, Inc. elsewhere on the record
- 5%+ stake filings Nov 2026
Companies that share a holder
- Cormorant Asset Management, LP also filed stake reports on 17 other companies: Corbus Pharmaceuticals Holdings, Inc. (Nov 2026), Adlai Nortye Ltd. (Aug 2026), BioAge Labs, Inc. (Aug 2026)
- ORBIS INVESTMENT MANAGEMENT LTD also filed stake reports on 23 other companies: RXO, Inc. (Nov 2026), National CineMedia, Inc. (Sep 2026), BBB FOODS INC (Aug 2026)
- Soleus Capital Master Fund, L.P. also filed stake reports on 24 other companies: Beta Bionics, Inc. (Nov 2026), Evolus, Inc (Nov 2026), INSPIRE MEDICAL SYSTEMS, INC. (Nov 2026)
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