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5%+ stakes · Schedule 13D and 13G

Tango Therapeutics Inc: 5%+ holders

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Who has reported owning 5% or more of Tango Therapeutics Inc, from Schedule 13D and 13G filings: each holder's stake as filed, the timeline, and the purpose each 13D states, quoted.

As of November 7, 2026, 8 holders' latest Schedule 13D or 13G filings report owning 5% or more of Tango Therapeutics Inc. The largest reported stake is Fmr LLC's, at 15%. 35 filings are on record since July 17, 2025 (Schedule 13G/A, November 6, 2026).

Third Rock Ventures IV, L.P. also filed stake reports on 1 other company ↓

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Key facts

  • · Reporting person: Fmr LLC · Sole voting: 25,285,740 · Shared voting: 0 · Sole dispositive: 25,286,624 · Shared dispositive: 0 · SCHEDULE 13G/A, 2026-11-06
  • · Reporting person: Farallon Capital Management, L.L.C. · Sole voting: 0 · Shared voting: 16,270,187 · Sole dispositive: 0 · Shared dispositive: 16,270,187 · SCHEDULE 13G/A, 2026-08-14
  • · Holder: The Goldman Sachs Group, Inc. · Percent: 6% · SCHEDULE 13G
  • · Holder: Woodline Partners LP · Percent: 2.5% · SCHEDULE 13G/A
  • · Holder: TCG Crossover GP II, LLC · Percent: 7% · SCHEDULE 13G/A
At 5% or more8
Filings35
Latest filing2026-11-06

Tango Therapeutics Inc has 35 Schedule 13D or 13G filings on record since 2025-07-17. 8 holders' latest filing reports 5% or more of common stock. Each figure below is the holder's own, as filed, with the filing linked.

Holders

HolderPercentSharesLatestEvent date
Fmr LLC15%25,286,624SCHEDULE 13G/A, 2026-11-062026-10-30
9.99%13,461,215SCHEDULE 13G/A, 2026-02-062025-12-31
Farallon Capital Management, L.L.C.9.8%16,270,187SCHEDULE 13G/A, 2026-08-142026-06-30
RTW Investments, LP9.3%13,300,620SCHEDULE 13G, 2026-05-152026-03-31
7.8%11,257,203SCHEDULE 13G/A, 2026-05-112026-03-31
TCG Crossover GP II, LLC7%10,147,867SCHEDULE 13G/A, 2026-08-142026-06-30
BlackRock, Inc.6.3%8,477,165SCHEDULE 13G, 2026-01-212025-12-31
The Goldman Sachs Group, Inc.6%9,742,403SCHEDULE 13G, 2026-08-142026-06-30
Third Rock Ventures IV, L.P.4.74%6,374,574SCHEDULE 13D/A, 2026-02-102026-02-06
4%5,657,105SCHEDULE 13G/A, 2026-05-042026-03-31
Adage Capital Management, L.P.3.44%5,600,000SCHEDULE 13G/A, 2026-08-122026-06-30
Woodline Partners LP2.5%4,000,567SCHEDULE 13G/A, 2026-08-142026-06-30
The Vanguard Group0%0SCHEDULE 13G/A, 2026-03-272026-03-13
EcoR1 Capital, LLC0%0SCHEDULE 13G/A, 2026-02-172025-12-31
Nextech Crossover I GP S.a. r.l.0%0SCHEDULE 13G/A, 2026-08-142026-06-30

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Keep reading

More on Tango Therapeutics Inc and the records around it.

Tango Therapeutics Inc elsewhere on the record

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Example from a real report (our sample on Target): “The Q2 2026 earnings report, published August 19, 2026, showed adjusted EPS of $2.46 against an expected $2.33” Source: CNBC

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Voting and dispositive power, as filed

Reporting personSole votingShared votingSole dispositiveShared dispositiveFiling
Fmr LLC25,285,740025,286,6240SCHEDULE 13G/A, 2026-11-06
Abigail P. Johnson0025,286,6240SCHEDULE 13G/A, 2026-11-06
Farallon Capital Management, L.L.C.016,270,187016,270,187SCHEDULE 13G/A, 2026-08-14
Farallon Capital Partners, L.P.0000SCHEDULE 13G/A, 2026-08-14
Farallon Capital Institutional Partners, L.P.0000SCHEDULE 13G/A, 2026-08-14
Farallon Capital Institutional Partners II, L.P.0000SCHEDULE 13G/A, 2026-08-14
Farallon Capital Institutional Partners III, L.P.0000SCHEDULE 13G/A, 2026-08-14
Four Crossings Institutional Partners V, L.P.0000SCHEDULE 13G/A, 2026-08-14
Farallon Capital Offshore Investors II, L.P.0000SCHEDULE 13G/A, 2026-08-14
Farallon Capital (AM) Investors, L.P.0000SCHEDULE 13G/A, 2026-08-14
Farallon Capital F5 Master I, L.P.0000SCHEDULE 13G/A, 2026-08-14
Farallon Healthcare Partners Master, L.P.0000SCHEDULE 13G/A, 2026-08-14
Farallon Partners, L.L.C.0000SCHEDULE 13G/A, 2026-08-14
Farallon Institutional (GP) V, L.L.C.0000SCHEDULE 13G/A, 2026-08-14
Farallon F5 (GP), L.L.C.0000SCHEDULE 13G/A, 2026-08-14
Farallon Healthcare Partners (GP), L.L.C.0000SCHEDULE 13G/A, 2026-08-14
Dapice Joshua J.016,270,187016,270,187SCHEDULE 13G/A, 2026-08-14
Dreyfuss, Philip D.016,270,187016,270,187SCHEDULE 13G/A, 2026-08-14
Dunn Hannah E.016,270,187016,270,187SCHEDULE 13G/A, 2026-08-14
Gehani, Varun N.016,270,187016,270,187SCHEDULE 13G/A, 2026-08-14
Giauque, Nicolas016,270,187016,270,187SCHEDULE 13G/A, 2026-08-14
Husen, Avner A.016,270,187016,270,187SCHEDULE 13G/A, 2026-08-14
Kim, David T.016,270,187016,270,187SCHEDULE 13G/A, 2026-08-14
Linn, Michael G.016,270,187016,270,187SCHEDULE 13G/A, 2026-08-14

The latest filing identifies Tango Therapeutics Inc by CUSIP 87583X109 and gives its principal executive office as 201 BROOKLINE AVENUE, SUITE 901, BOSTON, MA 02215 (SCHEDULE 13G/A, 2026-11-06).

Timeline

FiledHolderPercentFiling
2025-07-17BlackRock, Inc.5%SCHEDULE 13G
2025-08-12Adage Capital Management, L.P.5.45%SCHEDULE 13G
2025-08-13Dapice Joshua J.8.4%SCHEDULE 13G/A
2025-08-14Woodline Partners LP5.6%SCHEDULE 13G
2025-09-22Raymond Debbane5.3%SCHEDULE 13G
2025-11-12Dapice Joshua J.9.7%SCHEDULE 13G/A
2025-11-13Adage Capital Management, L.P.2.26%SCHEDULE 13G/A
2025-11-14Third Rock Ventures IV, L.P.6.97%SCHEDULE 13D/A
2025-11-14TCG Crossover GP II, LLC6.3%SCHEDULE 13G/A
2025-11-21Third Rock Ventures IV, L.P.5.85%SCHEDULE 13D/A
2026-01-21BlackRock, Inc.6.3%SCHEDULE 13G
2026-01-30The Vanguard Group5.01%SCHEDULE 13G
2026-02-06Dapice Joshua J.9.99%SCHEDULE 13G/A
2026-02-10Third Rock Ventures IV, L.P.4.74%SCHEDULE 13D/A
2026-02-12Adage Capital Management, L.P.7.88%SCHEDULE 13G
2026-02-13Raymond Debbane6.1%SCHEDULE 13G/A
2026-02-17Woodline Partners LP7.5%SCHEDULE 13G/A
2026-02-17EcoR1 Capital, LLC0%SCHEDULE 13G/A
2026-02-17TCG Crossover GP II, L.P.9.99%SCHEDULE 13G/A
2026-03-27The Vanguard Group0%SCHEDULE 13G/A
2026-05-04Raymond Debbane4%SCHEDULE 13G/A
2026-05-06Fmr LLC6.9%SCHEDULE 13G
2026-05-11Dapice Joshua J.7.8%SCHEDULE 13G/A
2026-05-13Adage Capital Management, L.P.8.98%SCHEDULE 13G/A
2026-05-15Woodline Partners LP5.6%SCHEDULE 13G/A
2026-05-15TCG Crossover GP II, LLC8.1%SCHEDULE 13G/A
2026-05-15RTW Investments, LP9.3%SCHEDULE 13G
2026-05-15Nextech Crossover I GP S.a. r.l.5.1%SCHEDULE 13G/A
2026-08-12Adage Capital Management, L.P.3.44%SCHEDULE 13G/A
2026-08-14The Goldman Sachs Group, Inc.6%SCHEDULE 13G
2026-08-14Farallon Capital Management, L.L.C.9.8%SCHEDULE 13G/A
2026-08-14Woodline Partners LP2.5%SCHEDULE 13G/A
2026-08-14TCG Crossover GP II, LLC7%SCHEDULE 13G/A
2026-08-14Nextech Crossover I GP S.a. r.l.0%SCHEDULE 13G/A
2026-11-06Fmr LLC15%SCHEDULE 13G/A

Questions about who owns Tango Therapeutics Inc

Who owns Tango Therapeutics Inc?

On this page, 8 holders' latest ownership filings report 5% or more of Tango Therapeutics Inc: Fmr LLC (15%, Schedule 13G/A, filed 2026-11-06), Dapice Joshua J. (9.99%, Schedule 13G/A, filed 2026-02-06), Farallon Capital Management, L.L.C. (9.8%, Schedule 13G/A, filed 2026-08-14), RTW Investments, LP (9.3%, Schedule 13G, filed 2026-05-15) and Dapice Joshua J. (7.8%, Schedule 13G/A, filed 2026-05-11); 3 more are listed above.

Who are the largest shareholders of Tango Therapeutics Inc?

By the share each holder's latest filing reports, the largest holders of Tango Therapeutics Inc on this page are Fmr LLC (15%), Dapice Joshua J. (9.99%) and Farallon Capital Management, L.L.C. (9.8%).

When did Fmr LLC buy into Tango Therapeutics Inc?

The filings give report dates, not purchase dates. The earliest filing from Fmr LLC on this page is the Schedule 13G, filed 2026-05-06, reporting 6.9%; its latest, Schedule 13G/A filed 2026-11-06, reports 15%.

Is this an audit or a full list?

Neither. The ownership list on this page covers only Schedule 13D and 13G filings, which holders make once they own 5% or more of a class of shares (an amendment can report a stake that has since fallen below 5%); 35 such filings are shown here. It is not an audit and not a full cap table: holders who never reached 5% are not listed, and a stake can change after its latest filing.

Also on the record for Tango Therapeutics Inc

DateRecordFigureOur pageSource
August 6, 2026Leadership change filing (Form 8-K, Item 5.02)—Leadership changesSource
June 23, 2026Leadership change: Robert Azelby appointed, Director—Leadership changesSource
May 13, 2026Leadership change: Alexis Borisy departs, Lead Independent Director, and 1 more—Leadership changesSource
April 15, 2026Leadership change: Matthew Gall appointed, Chief Financial Officer, and 1 more—Leadership changesSource
October 28, 2025Form D, private offering$15M soldForm D pageSource

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Where this comes from

Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.

Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.

Cite this page

Permanent URL: https://mentionfox.com/stakes/tango-therapeutics
Last updated 2026-11-07
Primary record: SEC filing 1 · SEC filing 2 · SEC filing 3 · SEC filing 4
Who owns 5% or more of Tango Therapeutics Inc? 8 holders at 5% or more, largest Fmr LLC 15%. MentionFox, 2026-11-07. https://mentionfox.com/stakes/tango-therapeutics