As of November 8, 2026, 5 holders' latest Schedule 13D or 13G filings report owning 5% or more of SCYNEXIS, Inc. The largest reported stake is Great Point Partners, LLC's, at 9.99%. 15 filings are on record since October 7, 2025 (Schedule 13G/A, August 14, 2026).
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Key facts
- · Reporting person: Great Point Partners, LLC · Sole voting: 0 · Shared voting: 4,076,068 · Sole dispositive: 0 · Shared dispositive: 4,076,068 · SCHEDULE 13G/A, 2026-08-14
- · Reporting person: CVI Investments, Inc. · Sole voting: 0 · Shared voting: 615,522 · Sole dispositive: 0 · Shared dispositive: 615,522 · SCHEDULE 13G/A, 2026-08-14
- · Reporting person: Adage Capital Management, L.P. · Sole voting: 0 · Shared voting: 1,041,824 · Sole dispositive: 0 · Shared dispositive: 1,041,824 · SCHEDULE 13G, 2026-08-12
- · Reporting person: Federated Hermes, Inc. · Sole voting: 441,658 · Shared voting: 0 · Sole dispositive: 441,658 · Shared dispositive: 0 · SCHEDULE 13G/A, 2026-07-20
- · Holder: Federated Hermes, Inc. · Percent: 4.45% · SCHEDULE 13G/A
SCYNEXIS, Inc. has 15 Schedule 13D or 13G filings on record since 2025-10-07. 5 holders' latest filing reports 5% or more of common stock, $0.001 par value per share. Each figure below is the holder's own, as filed, with the filing linked.
Holders
| Holder | Percent | Shares | Latest | Event date |
|---|---|---|---|---|
| Great Point Partners, LLC | 9.99% | 4,076,068 | SCHEDULE 13G/A, 2026-08-14 | 2026-06-30 |
| Adage Capital Management, L.P. | 9.99% | 1,041,824 | SCHEDULE 13G, 2026-08-12 | 2026-06-30 |
| Avidity Partners Management LP | 9.9% | 4,426,565 | SCHEDULE 13G/A, 2026-02-17 | 2025-12-31 |
| Squadron Master Fund LP | 9.6% | 7,608,695 | SCHEDULE 13G, 2026-04-08 | 2026-03-31 |
| CVI Investments, Inc. | 5.9% | 615,522 | SCHEDULE 13G/A, 2026-08-14 | 2026-06-30 |
| Federated Hermes, Inc. | 4.03% | 441,658 | SCHEDULE 13G/A, 2026-07-20 | 2026-06-30 |
| Kingdon Capital Management, L.L.C. | 0% | 0 | SCHEDULE 13G/A, 2026-02-17 | 2025-12-31 |
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More on SCYNEXIS, Inc. and the records around it.
SCYNEXIS, Inc. elsewhere on the record
- Leadership changes Sep 2026
- Who owns it
Companies that share a holder
- Kingdon Capital Management, L.L.C. also filed stake reports on 2 other companies: enVVeno Medical Corporation (May 2026), Jasper Therapeutics, Inc. (Nov 2025)
- Avidity Partners Management LP also filed stake reports on 5 other companies: Context Therapeutics Inc. (May 2026), Immunic, Inc. (Apr 2026), Perspective Therapeutics, Inc. (Mar 2026)
- Federated Hermes, Inc. also filed stake reports on 13 other companies: EyePoint (Nov 2026), Arcturus Therapeutics Holdings Inc. (Oct 2026), Forte Biosciences, Inc. (Sep 2026)
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Voting and dispositive power, as filed
| Reporting person | Sole voting | Shared voting | Sole dispositive | Shared dispositive | Filing |
|---|---|---|---|---|---|
| Great Point Partners, LLC | 0 | 4,076,068 | 0 | 4,076,068 | SCHEDULE 13G/A, 2026-08-14 |
| Dr. Jeffrey R. Jay, M.D. | 0 | 4,076,068 | 0 | 4,076,068 | SCHEDULE 13G/A, 2026-08-14 |
| Ms. Lillian Nordahl | 0 | 4,076,068 | 0 | 4,076,068 | SCHEDULE 13G/A, 2026-08-14 |
| Adage Capital Management, L.P. | 0 | 1,041,824 | 0 | 1,041,824 | SCHEDULE 13G, 2026-08-12 |
| Robert Atchinson | 0 | 1,041,824 | 0 | 1,041,824 | SCHEDULE 13G, 2026-08-12 |
| Phillip Gross | 0 | 1,041,824 | 0 | 1,041,824 | SCHEDULE 13G, 2026-08-12 |
| CVI Investments, Inc. | 0 | 615,522 | 0 | 615,522 | SCHEDULE 13G/A, 2026-08-14 |
| Heights Capital Management, Inc. | 0 | 615,522 | 0 | 615,522 | SCHEDULE 13G/A, 2026-08-14 |
| Federated Hermes, Inc. | 441,658 | 0 | 441,658 | 0 | SCHEDULE 13G/A, 2026-07-20 |
| Voting Shares Irrevocable Trust | 441,658 | 0 | 441,658 | 0 | SCHEDULE 13G/A, 2026-07-20 |
| Thomas R. Donahue | 0 | 441,658 | 0 | 441,658 | SCHEDULE 13G/A, 2026-07-20 |
| Ann C. Donahue | 0 | 441,658 | 0 | 441,658 | SCHEDULE 13G/A, 2026-07-20 |
| J. Christopher Donahue | 0 | 441,658 | 0 | 441,658 | SCHEDULE 13G/A, 2026-07-20 |
The latest filing identifies SCYNEXIS, Inc. by CUSIP 811292309 and gives its principal executive office as 1 Evertrust Plaza, 13th Floor, Jersey City, NJ 07302-6548 (SCHEDULE 13G/A, 2026-08-14).
Timeline
| Filed | Holder | Percent | Filing |
|---|---|---|---|
| 2025-10-07 | Federated Hermes, Inc. | 11.26% | SCHEDULE 13G/A |
| 2025-11-12 | Kingdon Capital Management, L.L.C. | 5.3% | SCHEDULE 13G/A |
| 2025-11-14 | Avidity Partners Management LP | 9.9% | SCHEDULE 13G/A |
| 2026-01-08 | Federated Hermes, Inc. | 8.42% | SCHEDULE 13G/A |
| 2026-02-17 | Kingdon Capital Management, L.L.C. | 0% | SCHEDULE 13G/A |
| 2026-02-17 | Avidity Partners Management LP | 9.9% | SCHEDULE 13G/A |
| 2026-04-07 | Great Point Partners, LLC | 9.99% | SCHEDULE 13G |
| 2026-04-08 | Squadron Master Fund LP | 9.6% | SCHEDULE 13G |
| 2026-04-28 | CVI Investments, Inc. | 6.7% | SCHEDULE 13G |
| 2026-05-15 | CVI Investments, Inc. | 6.2% | SCHEDULE 13G/A |
| 2026-07-08 | Federated Hermes, Inc. | 4.45% | SCHEDULE 13G/A |
| 2026-07-20 | Federated Hermes, Inc. | 4.03% | SCHEDULE 13G/A |
| 2026-08-12 | Adage Capital Management, L.P. | 9.99% | SCHEDULE 13G |
| 2026-08-14 | Great Point Partners, LLC | 9.99% | SCHEDULE 13G/A |
| 2026-08-14 | CVI Investments, Inc. | 5.9% | SCHEDULE 13G/A |
Questions about who owns SCYNEXIS, Inc.
Who owns SCYNEXIS, Inc.?
On this page, 5 holders' latest ownership filings report 5% or more of SCYNEXIS, Inc.: Great Point Partners, LLC (9.99%, Schedule 13G/A, filed 2026-08-14), Adage Capital Management, L.P. (9.99%, Schedule 13G, filed 2026-08-12), Avidity Partners Management LP (9.9%, Schedule 13G/A, filed 2026-02-17), Squadron Master Fund LP (9.6%, Schedule 13G, filed 2026-04-08) and CVI Investments, Inc. (5.9%, Schedule 13G/A, filed 2026-08-14).
Who are the largest shareholders of SCYNEXIS, Inc.?
By the share each holder's latest filing reports, the largest holders of SCYNEXIS, Inc. on this page are Great Point Partners, LLC (9.99%), Adage Capital Management, L.P. (9.99%) and Avidity Partners Management LP (9.9%).
When did Great Point Partners, LLC buy into SCYNEXIS, Inc.?
The filings give report dates, not purchase dates. The earliest filing from Great Point Partners, LLC on this page is the Schedule 13G, filed 2026-04-07, reporting 9.99%; its latest, Schedule 13G/A filed 2026-08-14, reports 9.99%.
Is this an audit or a full list?
Neither. The ownership list on this page covers only Schedule 13D and 13G filings, which holders make once they own 5% or more of a class of shares (an amendment can report a stake that has since fallen below 5%); 15 such filings are shown here. It is not an audit and not a full cap table: holders who never reached 5% are not listed, and a stake can change after its latest filing.
Also on the record for SCYNEXIS, Inc.
| Date | Record | Figure | Our page | Source |
|---|---|---|---|---|
| September 22, 2026 | Leadership change: Steven K. Burke appointed, Director, and 1 more | — | Leadership changes | Source |
| September 10, 2026 | Leadership change: Ivor Macleod departs, Chief Financial Officer, and 1 more | — | Leadership changes | Source |
| April 20, 2026 | Leadership change: Steven C. Gilman departs, Director | — | Leadership changes | Source |
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Where this comes from
Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.
Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.