About 75 employees are affected, according to Alector, Inc.'s latest layoff filing, on October 21, 2025. As of November 6, 2026, Alector, Inc. has reported this one exit or restructuring plan to the SEC on Form 8-K under Item 2.05. No WARN notice under its name is on file in the states covered here (Form 8-K, October 21, 2025).
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Alector, Inc. reported 1 exit or restructuring plan on Form 8-K under Item 2.05, 1 of 1 stating how many employees or positions are affected. Each fact below is the filing's own sentence, quoted and linked. No WARN notice under this company's name is on file in the states covered here.
Did Alector have layoffs in 2025? What its filings say
Alector, Inc. (CIK 1653087) reported 1 exit or restructuring plan to the SEC on Form 8-K under Item 2.05. The sentences below are quoted from the filings as written.
Form 8-K filed 2025-10-21
Employees affected
The Company initiated a reduction in force impacting approximately 75 employees across the organization.
Expected charges
Total incremental restructuring charges associated with the reduction in force are expected to be approximately $7.7 million.
Timing
Cash payments related to these expenses will be paid out and the reduction in force is expected to be completed during the first half of 2026.
Also on the record for Alector, Inc.
| Date | Record | Figure | Our page | Source |
|---|---|---|---|---|
| October 26, 2026 | Stake report, Schedule 13G, by RA Capital Management, L.P. | 5.1% of the class | 5%+ stakes | Source |
| October 23, 2026 | Stake report, Schedule 13G, by Deep Track Capital, LP | 8.61% of the class | 5%+ stakes | Source |
| September 18, 2026 | Stake report, Schedule 13G, by BVF PARTNERS L P/IL | 8.4% of the class | 5%+ stakes | Source |
| May 14, 2026 | Stake report, Schedule 13G/A, by Terrance G. McGuire | 4.7% of the class | 5%+ stakes | Source |
| April 27, 2026 | Stake report, Schedule 13G, by BlackRock, Inc. | 5.2% of the class | 5%+ stakes | Source |
| March 26, 2026 | Stake report, Schedule 13G/A, by The Vanguard Group | — | 5%+ stakes | Source |
| February 17, 2026 | Stake report, Schedule 13G/A, by RTW Investments, LP | — | 5%+ stakes | Source |
| February 6, 2026 | Stake report, Schedule 13G/A, by Arnon Rosenthal | 7.4% of the class | 5%+ stakes | Source |
| January 30, 2026 | Stake report, Schedule 13G/A, by The Vanguard Group | 6.32% of the class | 5%+ stakes | Source |
| January 21, 2026 | Stake report, Schedule 13G/A, by BlackRock, Inc. | 4.7% of the class | 5%+ stakes | Source |
| November 14, 2025 | Stake report, Schedule 13G, by Chen Yu | 9.2% of the class | 5%+ stakes | Source |
| November 14, 2025 | Stake report, Schedule 13G, by RTW Investments, LP | 6.9% of the class | 5%+ stakes | Source |
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More on Alector, Inc. and the records around it.
Alector, Inc. elsewhere on the record
- 5%+ stake filings Oct 2026
- Who owns it
Companies that share a holder
- TCG Crossover GP II, LLC also filed stake reports on 21 other companies: ALX Oncology Holdings Inc. (Aug 2026), First Tracks Biotherapeutics, Inc. (Aug 2026), Fulcrum Therapeutics, Inc. (Aug 2026)
- RTW Investments, LP also filed stake reports on 43 other companies: CG Oncology, Inc. (Aug 2026), iRhythm Holdings, Inc. (Aug 2026), Kailera Therapeutics, Inc. (Aug 2026)
- BIOTECHNOLOGY VALUE FUND L P also filed stake reports on 55 other companies: Frazier Life Sciences Acquisition Corp. II (Oct 2026), Olema Pharmaceuticals, Inc. (Oct 2026), Foghorn Therapeutics Inc. (Oct 2026)
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Public companies must also report to the SEC, on Form 8-K under Item 2.05, when they commit to an exit or restructuring plan that will cost them material charges, which is how most large layoffs and closures by listed companies are disclosed. Those filings are national, so they cover companies in every state. Each sentence shown from one is quoted exactly and linked to the filing; where a filing does not state a figure, none is shown.
Where this comes from
Employers covered by the federal WARN Act, and by the stricter laws some states add, must give written notice before a mass layoff or a site closure. The state labor department publishes those notices. Every row here is one of them, taken from that state's own published file and linked to it, so each figure can be checked at the source.
A notice states the employer, the location, the number of employees affected, and when the layoff or closure takes effect. It does not state a reason, and neither does this page. Where a company also appears in SEC filings under the same name and in the same state, its recorded fundraising is shown alongside, as a matter of record rather than as an explanation. New Jersey and Pennsylvania list a notice under the month it was posted or received, not the day, so their notices show a month. Tennessee gives the county rather than the city.
Who owns Alector, Inc.? Owners, funding and legal record
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