About 43 employees are affected, according to Adagio Medical Holdings, Inc.'s latest layoff filing, on September 23, 2026. Adagio Medical Holdings, Inc. trades on Nasdaq as ADGM; it was formerly Aja Holdco, Inc. As of November 6, 2026, Adagio Medical Holdings, Inc. has reported this one exit or restructuring plan to the SEC on Form 8-K under Item 2.05 (Form 8-K, September 23, 2026).
Adagio Medical Holdings, Inc. announced layoffs of about 43 employees on Sep 23. 12 companies announced layoffs this week.
Companies cutting jobs this week. Before you unlock: the company, the number of employees and what is inside. After: every way we found to reach the company. No individual is named in a layoff.
| Artiva Biotherapeutics, Inc. | announced layoffs | |
| Eos Energy Enterprises, Inc. | announced layoffs | |
| SOUNDHOUND AI, INC. | announced layoffs | |
| Portillo's Inc. | announced layoffs | |
| Acumen Pharmaceuticals, Inc. | announced layoffs of about 52 employees |
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Adagio Medical Holdings, Inc. reported 1 exit or restructuring plan on Form 8-K under Item 2.05, 1 of 1 stating how many employees or positions are affected. Each fact below is the filing's own sentence, quoted and linked. No WARN notice under this company's name is on file in the states covered here.
Did Adagio Medical have layoffs in 2026? What its filings say
Adagio Medical Holdings, Inc. (CIK 2006986) reported 1 exit or restructuring plan to the SEC on Form 8-K under Item 2.05. The sentences below are quoted from the filings as written.
Form 8-K filed 2026-09-23
Employees affected
As part of the plan, the Company will reduce its workforce by 25 of 43 full-time employees, effective September 23, 2026.
Expected charges
The Company estimates that it will incur approximately $1.3 million of cash expenditures, consisting primarily of one-time severance payments, benefits and other related costs (excluding non-cash charges associated with equity-based compensation).
Also on the record for Adagio Medical Holdings, Inc.
| Date | Record | Figure | Our page | Source |
|---|---|---|---|---|
| August 14, 2026 | Stake report, Schedule 13G/A, by ADAR1 Capital Management, LLC | 5.4% of the class | 5%+ stakes | Source |
| July 28, 2026 | Stake report, Schedule 13G/A, by Sio Capital Management, LLC | 3.15% of the class | 5%+ stakes | Source |
| May 15, 2026 | Stake report, Schedule 13G/A, by Perceptive Advisors LLC | 55.4% of the class | 5%+ stakes | Source |
| May 13, 2026 | Stake report, Schedule 13G/A, by Adage Capital Management, L.P. | 5.67% of the class | 5%+ stakes | Source |
| February 17, 2026 | Stake report, Schedule 13G, by ADAR1 Capital Management, LLC | 5.7% of the class | 5%+ stakes | Source |
| February 17, 2026 | Stake report, Schedule 13G, by Alyeska Investment Group, L.P. | 9.9% of the class | 5%+ stakes | Source |
| February 17, 2026 | Stake report, Schedule 13G/A, by Perceptive Advisors LLC | 57.5% of the class | 5%+ stakes | Source |
| February 11, 2026 | Stake report, Schedule 13G, by Sio Capital Management, LLC | 6.08% of the class | 5%+ stakes | Source |
| November 13, 2025 | Stake report, Schedule 13G/A, by Adage Capital Management, L.P. | 6.88% of the class | 5%+ stakes | Source |
| October 29, 2025 | Form D, private offering | $19M sold | Form D page | Source |
| August 26, 2025 | Stake report, Schedule 13G/A, by RA Capital Management, L.P. | 7.2% of the class | 5%+ stakes | Source |
| August 14, 2025 | Stake report, Schedule 13G/A, by RA Capital Management, L.P. | — | 5%+ stakes | Source |
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More on Adagio Medical Holdings, Inc. and the records around it.
Adagio Medical Holdings, Inc. elsewhere on the record
- 5%+ stake filings Aug 2026
- Form D filing Oct 2025
- Who owns it
Companies that share a holder
- Sio Capital Management, LLC also filed stake reports on 9 other companies: Enveric Biosciences, Inc. (Nov 2026), PMV Pharmaceuticals, Inc. (Jul 2026), Anteris Technologies Global Corp. (May 2026)
- ADAR1 Capital Management, LLC also filed stake reports on 29 other companies: InMed Pharmaceuticals, Inc. (Oct 2026), Tenax Therapeutics, Inc. (Sep 2026), Amanat Acquisition Corp. (Aug 2026)
- Perceptive Advisors LLC also filed stake reports on 57 other companies: Nautilus Biotechnology, Inc. (Nov 2026), Athira Pharma, Inc. (Oct 2026), IRulya Therapeutics Inc. (Oct 2026)
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Public companies must also report to the SEC, on Form 8-K under Item 2.05, when they commit to an exit or restructuring plan that will cost them material charges, which is how most large layoffs and closures by listed companies are disclosed. Those filings are national, so they cover companies in every state. Each sentence shown from one is quoted exactly and linked to the filing; where a filing does not state a figure, none is shown.
Where this comes from
Employers covered by the federal WARN Act, and by the stricter laws some states add, must give written notice before a mass layoff or a site closure. The state labor department publishes those notices. Every row here is one of them, taken from that state's own published file and linked to it, so each figure can be checked at the source.
A notice states the employer, the location, the number of employees affected, and when the layoff or closure takes effect. It does not state a reason, and neither does this page. Where a company also appears in SEC filings under the same name and in the same state, its recorded fundraising is shown alongside, as a matter of record rather than as an explanation. New Jersey and Pennsylvania list a notice under the month it was posted or received, not the day, so their notices show a month. Tennessee gives the county rather than the city.
Who owns Adagio Medical Holdings, Inc.? Owners, funding and legal record
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