National Science Foundation awarded Pumpkinseed Technologies Inc of Palo Alto, CA $1,249,115 under the SBIR program (Phase II), with work starting 2025-08-01 and running to 2027-07-31. It is one of 2 SBIR and STTR awards Pumpkinseed Technologies Inc received in the last two years, $1,602,319 in all. Each figure links to the federal record.
The award
| Recipient | Pumpkinseed Technologies Inc (Palo Alto, CA) |
|---|---|
| Awarding agency | National Science Foundation |
| Phase | Phase II |
| Amount obligated | $1,249,115 |
| Period of performance starts | 2025-08-01 |
| Period of performance ends | 2027-07-31 |
| Award number | 2507825 (grant, CFDA 47.084) |
| Assistance listing | 47.084, Technology, Innovation, and Partnerships |
| Place of performance | Palo Alto, Santa Clara County, CA |
| Signed | 2025-07-24 |
| Recipient registry id (UEI) | Y3J2KMX477W5 |
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What it is for
High-throughput de-novo peptide sequencing with metasurface optics
Funding actions on this award
| Date | Action | Modification | Amount |
|---|---|---|---|
| 2025-07-24 | New | 000 | $1,249,115 |
SBIR Phase II: High-throughput de-novo peptide sequencing with metasurface optics -the broader/commercial impact of this small business innovation research (SBIR) Phase II project is to understand and control the proteins that drive immune responses, in order to create improved immune-modulating medicines. Healthy and robust immune systems are able to identify diseased proteins and target them for elimination. However, as humans age or immune systems weaken, immune cells become less adept at recognizing diseased proteins. Cancer, neurodegeneration, and autoimmune disorders are driven in part by dysfunctional communication between immune cells and diseased cells. Yet, current knowledge about which proteins drive immune responses is extremely limited. The estimated number of possible proteins interacting between immune cells and diseased cells exceeds the number of stars in the visible universe, and current techniques to investigate these proteins can only see a small fraction. If these diseased proteins could be identified, they would provide the key insight needed to create improved medicines - spanning targeted cancer therapies, autoimmunity treatments, and even medicines that prevent neurodegeneration. Such insights could not only drive improved health-spans, but also reduce costs associated with ineffective treatments that do not properly target the diseased cells, and incre ...
From the federal award record.
Other SBIR and STTR awards to Pumpkinseed Technologies Inc
| Starts | Agency | Program | Amount | Project |
|---|---|---|---|---|
| 2025-06-19 | Department of Health and Human Services | SBIR Phase I | $353,204 | Dynamic, live-cell monitoring of t-cell states against presented peptides - the goal of th (record) |
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The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs set aside part of federal research budgets for small companies. Agencies award them in phases: Phase I tests whether an idea is feasible, Phase II funds development, and Phase III is follow-on work paid for outside the set-aside. STTR awards also require a research institution as a partner.
Every figure on this page is taken from the award's own federal record, linked beside it, as it stood when the page was built: the recipient, its address, the awarding agency and office, the amount obligated so far, the dates and the description. Phase and program are shown as the award's own description states them. The amount can grow later if the agency adds funding to the same award.