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Federal R&D award · SBIR Phase I

Biotherapeutics, Inc. SBIR Phase I award

Award R43AG102078, starting 2026-09-18. Every figure below is from the federal award record.

Department of Health and Human Services, through National Institutes of Health, awarded Biotherapeutics, Inc. of Blacksburg, VA $500,000 under the SBIR program (Phase I), with work starting 2026-09-18 and running to 2027-09-17. It is one of 7 SBIR and STTR awards Biotherapeutics, Inc. received in the last two years, $2,464,685 in all. Each figure links to the federal record.

The award

RecipientBiotherapeutics, Inc. (Blacksburg, VA)
Awarding agencyDepartment of Health and Human Services
Awarding officeNational Institutes of Health
PhasePhase I
Amount obligated$500,000
Period of performance starts2026-09-18
Period of performance ends2027-09-17
Award numberR43AG102078 (grant, CFDA 93.866)
Assistance listing93.866, Aging Research
Place of performanceBlacksburg, Montgomery County, VA
Recipient registry id (UEI)DKZNEQL174E3

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What it is for

Immunometabolic therapeutics for alzheimer's disease - immunometabolic therapeutics for alzheimer’s disease biotherapeutics inc (bti) is an emerging biotech company that synergistically combines the power of advanced com

Funding actions on this award

DateActionModificationAmount
2026-09-18New000$500,000
Immunometabolic therapeutics for alzheimer's disease - immunometabolic therapeutics for alzheimer’s disease biotherapeutics inc (bti) is an emerging biotech company that synergistically combines the power of advanced computational modeling with translational experimentation to accelerate the development of novel precision medicine therapeutics for inflammatory, autoimmune and neurodegenerative diseases. This SBIR application will characterize a new immunometabolic therapeutic target for alzheimer’s disease (alz). Our product: With the goal of developing first-in-class oral therapeutics that protect against neurodegeneration in alz, bti has designed a novel chemotype that targets the immune and metabolic dysregulation in the brain. Our product candidates provide protection from alz by regulating lipid metabolism and glial cell activation. Background: Alz is a neurodegenerative disorder that afflicts an estimated 6 million people in the u.s. With over $300 billion annually in associated healthcare costs. The only recent therapeutic approvals have been met with controversy due to a lack of perceived clinical benefit in pivotal trials. Thus, there is an unmet clinical need for safe and efficacious alz therapeutics. While alz is commonly associated with β-amyloid plaques and neurofibrillary tangles, pathological features also include increased inflammation and oxidative stress, dama ...

From the federal award record.

Other SBIR and STTR awards to Biotherapeutics, Inc.

StartsAgencyProgramAmountProject
2026-09-01Department of Health and Human ServicesSBIR Phase I$314,363Immunometabolic therapeutics for multiple sclerosis - immunometabolic therapeutics for mul (record)
2026-08-13Department of Health and Human ServicesSBIR Phase I$314,363Novel immunoregulatory therapeutics for bacterial gastritis - novel immunoregulatory thera (record)
2025-08-13Department of Health and Human ServicesSBIR Phase I$314,363Next-gen oral therapeutics for concomitant clostridioides difficile infection and ibd - ne (record)
2025-08-01Department of Health and Human ServicesSBIR Phase I$314,363Novel therapeutic for sle - novel therapeutic for sle biotherapeutics inc (bti) is a clini (record)
2025-07-01Department of Health and Human ServicesSBIR Phase I$359,625Next-gen oral therapeutics for type 2 diabetes - next-gen oral therapeutics for type 2 dia (record)
2025-02-01Department of Health and Human ServicesSBIR Phase I$347,608The next wave of asthma therapeutics - the next wave of asthma therapeutics biotherapeutic (record)
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Where this comes from

The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs set aside part of federal research budgets for small companies. Agencies award them in phases: Phase I tests whether an idea is feasible, Phase II funds development, and Phase III is follow-on work paid for outside the set-aside. STTR awards also require a research institution as a partner.

Every figure on this page is taken from the award's own federal record, linked beside it, as it stood when the page was built: the recipient, its address, the awarding agency and office, the amount obligated so far, the dates and the description. Phase and program are shown as the award's own description states them. The amount can grow later if the agency adds funding to the same award.

Cite this page

Permanent URL: https://mentionfox.com/grants/biotherapeutics-r43ag102078
Last updated 2026-09-30
Primary record: Federal award record
Biotherapeutics, Inc.: $500,000 SBIR Phase I award from HHS (2026). MentionFox, 2026-09-30. https://mentionfox.com/grants/biotherapeutics-r43ag102078