Department of Health and Human Services, through National Institutes of Health, awarded Amygo Solutions LLC of Grand Prairie, TX $329,469 under the SBIR program (Phase I), with work starting 2026-09-05 and running to 2027-08-31. It is one of 2 SBIR and STTR awards Amygo Solutions LLC received in the last two years, $634,112 in all. Each figure links to the federal record.
The award
| Recipient | Amygo Solutions LLC (Grand Prairie, TX) |
|---|---|
| Awarding agency | Department of Health and Human Services |
| Awarding office | National Institutes of Health |
| Phase | Phase I |
| Amount obligated | $329,469 |
| Period of performance starts | 2026-09-05 |
| Period of performance ends | 2027-08-31 |
| Award number | R43HL186878 (grant, CFDA 93.837) |
| Assistance listing | 93.837, Cardiovascular Diseases Research |
| Place of performance | Grand Prairie, Dallas County, TX |
| Signed | 2026-09-04 |
| Recipient registry id (UEI) | KXZGDHWW3RA6 |
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What it is for
Development of a blood-based diagnostic test for attr amyloidosis - project summary cardiac transthyretin amyloidosis (attr) is a progressive and underdiagnosed form of heart failure caused by the aggregation of misfolde
Funding actions on this award
| Date | Action | Modification | Amount |
|---|---|---|---|
| 2026-09-04 | New | 000 | $329,469 |
Development of a blood-based diagnostic test for attr amyloidosis - project summary cardiac transthyretin amyloidosis (attr) is a progressive and underdiagnosed form of heart failure caused by the aggregation of misfolded transthyretin (ttr) protein into amyloid fibrils. This disease is estimated to contribute to over 500,000 heart failure-related deaths annually. Despite the availability of five fda-approved therapeutics, most effective when administered early, diagnosis is often delayed by 3–7 years due to reliance on specialized technicians and subjective interpretation of biopsy or imaging results, introducing variability and increasing operational burden. There are currently no blood-based tests available for early detection of attr, and average diagnostic costs exceed $100,000 per patient. Amygo solutions has developed a blood-based assay leveraging a proprietary biomarker, circulating misfolded ttr aggregates, that appears early in disease, is absent in healthy individuals, and confers information on treatment response. The company’s platform uses a structure-guided peptide, transthyretin aggregation detector 1 (TAD1), which selectively binds pathogenic ttr aggregates. This Phase I SBIR project aims to develop and validate a TAD1-BASED assay kit for automated, low-cost detection of attr that is compatible with clinical laboratory workflows. Aim 1 will involve designing, ...
From the federal award record.
Other SBIR and STTR awards to Amygo Solutions LLC
| Starts | Agency | Program | Amount | Project |
|---|---|---|---|---|
| 2026-07-01 | National Science Foundation | SBIR Phase I | $304,643 | Development of a blood test for the detection of transthyretin amyloidosis (record) |
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Get the free SnapshotWhere this comes from
The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs set aside part of federal research budgets for small companies. Agencies award them in phases: Phase I tests whether an idea is feasible, Phase II funds development, and Phase III is follow-on work paid for outside the set-aside. STTR awards also require a research institution as a partner.
Every figure on this page is taken from the award's own federal record, linked beside it, as it stood when the page was built: the recipient, its address, the awarding agency and office, the amount obligated so far, the dates and the description. Phase and program are shown as the award's own description states them. The amount can grow later if the agency adds funding to the same award.
