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Matrubials (YC S21) — Developing milk-inspired therapeutics for infectious diseases

Matrubials is an anti-infectives company, focused on human milk peptides as therapeutics to address antimicrobial resistance and modern diseases. Currently the global rise in severe bacterial infections and the drying pipeline of effective treatments are burdensome for healthcare and economics.

Matrubials is a Y Combinator company in the Summer 2021 batch. Its directory entry describes it as: Developing milk-inspired therapeutics for infectious diseases. The founders listed are Bruce German (Founder), Carlito Lebrilla (Founder), David Mills (Founder) (Y Combinator directory entry, July 6, 2021).

6 more companies from YC Summer 2021 ↓

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Matrubials

New accelerator entry · 2021-07-06 · the record

Summer 2021
batch
4
people
Early
stage
United States of America
region
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What the record says

BatchSummer 2021
Announced2021-07-06
StageEarly
StatusActive
Team size4
IndustryHealthcare
Sub-industryHealthcare -> Drug Discovery and Delivery
SectorsAI-powered Drug Discovery, Women's Health, Therapeutics
RegionsUnited States of America, America / Canada
BasedDavis, CA, USA
HiringNo
Sitehttps://matrubials.com/
Previously known asMatrubials Inc.

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Also in YC Summer 2021

Same batch, Healthcare first.

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In their words

Matrubials is an anti-infectives company, focused on human milk peptides as therapeutics to address antimicrobial resistance and modern diseases. Currently the global rise in severe bacterial infections and the drying pipeline of effective treatments are burdensome for healthcare and economics. Sculpted by evolution, milk, first food for the newborn, provides an exemplary solution to address the nutritive and protective challenges an infant is faced with. The anti-pathogenic molecules from milk can be developed into therapeutics geared towards all-age diseases. Our first indication is bacterial vaginosis, a bacterial dysbiosis related inflammation that results in recurrent infections, disruption of homeostasis and long-term clinical complications in women of reproductive age, including but not limited to preterm births, fertility issues and increased rates of STDs. Our next inflection point is the evaluation of rapidly acting and selective candidate peptides in pre-clinical host impact and early safety studies, which can aid clinical and portfolio development towards topical applications.

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Matrubials: Accepted into Y Combinator Summer 2021
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Permanent URL: https://mentionfox.com/funding/yc-matrubials-inc
Last updated 2026-10-20
Primary record: Y Combinator directory entry
Matrubials (YC S21) — Developing milk-inspired therapeutics for infectious diseases. MentionFox, 2026-10-20. https://mentionfox.com/funding/yc-matrubials-inc