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Abalone Bio (YC W20) — We create activating antibodies to treat diseases others can’t

Abalone Bio appears in Y Combinator's company directory in the Winter 2020 batch, listed 2020-03-11. We create activating antibodies to treat diseases others can’t..

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Abalone Bio: Accepted into Y Combinator Winter 2020

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Abalone Bio

New accelerator entry · 2020-03-11 · the record

Winter 2020
batch
14
people
Early
stage
United States of America
region
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In their words

Abalone Bio is tackling challenging undrugged targets underlying diseases affecting millions, focusing first cell-specific antibody drugs to treat obesity and metabolic disease without the GI side effects that cause 25% of GLP-1 drug patients to quit after 1 year. + High throughput experimental measurement uniquely leverages AI/ML: We’ve engineered cells to measure antibodies for pharmacological activity, not just structure or binding like others, 100 million at a time, 100X+ the throughput of others. With our large, proprietary activity datasets, we uniquely leverage ML to both unlock the discovery of rare hits and generate optimized hits for challenging targets, starting with G-protein coupled receptors (GPCRs) + Proven success: We have developed antibody agonists (activators) for 2 out of the 8 G-protein coupled receptors ever drugged by biotech. + Pharma traction: We’ve secured 3 partnerships with $3M in revenue and $125M in downstream value. + Externally validated science: We’ve been awarded $7M in non-dilutive grant funding for platform and program development.

What the record says

BatchWinter 2020
Announced2020-03-11
StageEarly
StatusActive
Team size14
IndustryHealthcare
Sub-industryHealthcare -> Drug Discovery and Delivery
SectorsMachine Learning, Synthetic Biology, Therapeutics, Drug discovery
RegionsUnited States of America, America / Canada
BasedSan Francisco, CA, USA
HiringNo
Sitehttps://www.abalonebio.com
Previously known asAbalone Bio, Inc

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Permanent URL: https://mentionfox.com/funding/yc-abalone-bio
Last updated 2026-09-26
Primary record: Y Combinator directory entry
Abalone Bio (YC W20) — We create activating antibodies to treat diseases others can’t. MentionFox, 2026-09-26. https://mentionfox.com/funding/yc-abalone-bio