As of November 6, 2026, Prime Medicine, Inc. is a publicly traded company (Nasdaq: PRME). The largest holder reporting an active stake on Schedule 13D is ARCH Venture Fund XII, L.P., at 10.4%. No bankruptcy or receivership appears in its SEC Form 8-K filings. Passive holders reporting on Schedule 13G include Alphabet Holdings LLC (12.3%) (Schedule 13D/A, August 11, 2025).
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Is Prime Medicine, Inc. a real, registered company?
- Prime Medicine, Inc. files with the SEC under CIK 1894562 (its SEC filings).
- Its shares are listed under the ticker PRME on Nasdaq (SEC company record).
- Incorporated in Delaware; business address in Cambridge, Massachusetts, as its SEC filings state.
- Court and bankruptcy records: see Before you sign or pay below.
Before you sign or pay
- Court and bankruptcy: No federal court case or bankruptcy filing found under PRIME MEDICINE INC in our court records and SEC 8-K records (as of 2026-11-06).
- Leadership changes: the latest reported is Svetlana Makhni, Chief Financial Officer (Form 8-K filed 2026-04-16). Check you are dealing with the people now in charge.
- Ownership: 5%+ holders are reported on Schedule 13D or 13G; the latest names T. Rowe Price (filed 2025-11-14).
Who are Prime Medicine, Inc.'s owners and officers?
Prime Medicine, Inc.: incorporated in Delaware; business address in Cambridge, Massachusetts; industry Biological Products, (No Diagnostic Substances) (Form D, 2026-04-16).
| Report | Holder | Share |
|---|---|---|
| Schedule 13G/A, 2026-02-17 | T. Rowe Price Investment Management, Inc. | 3.3% |
| Schedule 13G, 2025-11-14 | T. Rowe Price Investment Management, Inc. | 5.3% |
| Schedule 13G/A, 2025-11-12 | Alphabet Holdings LLC | 12.3% |
| Schedule 13G/A, 2025-11-05 | Fmr LLC | 3.8% |
| Schedule 13D/A, 2025-08-11 | Arch Venture Fund Xii, L.P. | 10.4% |
Questions about who owns Prime Medicine, Inc.
Who owns Prime Medicine, Inc.?
On this page, 2 holders' latest ownership filings report 5% or more of Prime Medicine, Inc.: Alphabet Holdings LLC (12.3%, Schedule 13G/A, filed 2025-11-12) and Arch Venture Fund Xii, L.P. (10.4%, Schedule 13D/A, filed 2025-08-11).
Who are the largest shareholders of Prime Medicine, Inc.?
By the share each holder's latest filing reports, the largest holders of Prime Medicine, Inc. on this page are Alphabet Holdings LLC (12.3%) and Arch Venture Fund Xii, L.P. (10.4%).
When did Alphabet Holdings LLC buy into Prime Medicine, Inc.?
The filings give report dates, not purchase dates. The earliest filing from Alphabet Holdings LLC on this page is the Schedule 13G/A, filed 2025-11-12, reporting 12.3%. That earliest filing is itself an amendment, which updates an earlier report.
Is this an audit or a full list?
Neither. The ownership list on this page covers only Schedule 13D and 13G filings, which holders make once they own 5% or more of a class of shares (an amendment can report a stake that has since fallen below 5%); 5 such filings are shown here. It is not an audit and not a full cap table: holders who never reached 5% are not listed, and a stake can change after its latest filing.
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| Filed | Person | Role | Change | Effective |
|---|---|---|---|---|
| Form 8-K, 2026-04-16 | Svetlana Makhni | Chief Financial Officer | appointed | 2026-04-16 |
Which insiders own Prime Medicine, Inc. shares?
Directors, officers and holders of 10% or more report their shares on Forms 3, 4 and 5. Each line is the latest such report, largest holding first.
- , a 10% owner: 20,240,945 shares (11.2% of shares outstanding) (Form 4, 2025-07-01).
- , a director and 10% owner: 18,502,974 shares (10.2% of shares outstanding), held indirectly through By ARCH Venture Fund XII, L.P. and 1 other (Form 4, 2025-08-01).
- ARCH Venture Partners XII, L.P., a 10% owner: 18,486,894 shares (10.2% of shares outstanding), held indirectly through By ARCH Venture Fund XII, L.P. and 2 others, on a joint filing (Form 4, 2025-08-01).
- ARCH Venture Fund XII, L.P., a 10% owner: 18,486,894 shares (10.2% of shares outstanding), held indirectly through By ARCH Venture Fund XII, L.P. and 2 others, on a joint filing (Form 4, 2025-08-01).
- ARCH Venture Partners XII, LLC, a 10% owner: 18,486,894 shares (10.2% of shares outstanding), held indirectly through By ARCH Venture Fund XII, L.P. and 2 others, on a joint filing (Form 4, 2025-08-01).
Shares outstanding: 181,376,856 as of 2026-07-31, from the company's latest SEC cover page.
How much has Prime Medicine, Inc. raised?
No fundraising or offering filing from Prime Medicine, Inc. is on file with us.
Keep reading
More on Prime Medicine, Inc. and the records around it.
Prime Medicine, Inc. elsewhere on the record
- Leadership changes Apr 2026
- 5%+ stake filings Feb 2026
Companies that share a holder
- GV 2019, L.P. also filed stake reports on 2 other companies: Ethos Technologies Inc. (Nov 2026), MAZE THERAPEUTICS, INC. (Feb 2026)
- ARCH Venture Fund X, L.P. also filed stake reports on 5 other companies: City Therapeutics, Inc. (Oct 2026), Parabilis Medicines, Inc. (Aug 2026), Seaport Therapeutics, Inc. (May 2026)
- T. Rowe Price Investment Management, Inc. also filed stake reports on 167 other companies: CABALETTA BIO INC (Nov 2026), MADISON SQUARE GARDEN SPORTS CORP (Nov 2026), MSG RANGERS CORP (Nov 2026)
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