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5%+ stakes · Schedule 13D and 13G

Xilio Therapeutics, Inc.: 5%+ holders

Who has reported owning 5% or more of Xilio Therapeutics, Inc., from Schedule 13D and 13G filings: each holder's stake as filed, the timeline, and the purpose each 13D states, quoted.

At 5% or more7
Filings14
Latest filing2026-08-14

Xilio Therapeutics, Inc. has 14 Schedule 13D or 13G filings on record since 2025-08-14. 7 holders' latest filing reports 5% or more of common stock, par value $0.0001 per share. Each figure below is the holder's own, as filed, with the filing linked.

Holders

HolderPercentSharesLatestEvent date
Gilead Sciences, Inc.19.9%14,517,678SCHEDULE 13G/A, 2026-02-122025-12-31
Coastlands Capital LP9.99%5,346,069SCHEDULE 13G, 2025-12-112025-12-04
BCLS II Equity Opportunities, LP9.99%664,021SCHEDULE 13G/A, 2026-05-152026-03-31
Orbimed Advisors LLC9.99%642,000SCHEDULE 13G, 2026-05-152026-03-31
Sirenia Capital Management LP9.9%1,142,862SCHEDULE 13G, 2026-05-152026-03-31
StemPoint Capital LP9.5%628,866SCHEDULE 13G/A, 2026-08-142026-06-30
Frazier Life Sciences Public Fund, L.P.6.7%4,676,472SCHEDULE 13G/A, 2026-02-132025-12-31
Point72 Asset Management, L.P.0%0SCHEDULE 13G/A, 2026-05-152026-03-31

Timeline

FiledHolderPercentFiling
2025-08-14Gilead Sciences, Inc.19.9%SCHEDULE 13G/A
2025-08-14Frazier Life Sciences Public Fund, L.P.9.9%SCHEDULE 13G/A
2025-11-14Point72 Asset Management, L.P.9.9%SCHEDULE 13G/A
2025-11-14StemPoint Capital LP7.2%SCHEDULE 13G
2025-12-11Coastlands Capital LP9.99%SCHEDULE 13G
2026-02-12Gilead Sciences, Inc.19.9%SCHEDULE 13G/A
2026-02-13Frazier Life Sciences Public Fund, L.P.6.7%SCHEDULE 13G/A
2026-02-17StemPoint Capital LP8.4%SCHEDULE 13G/A
2026-02-17BCLS II Equity Opportunities, LP8.5%SCHEDULE 13G/A
2026-05-15Sirenia Capital Management LP9.9%SCHEDULE 13G
2026-05-15Point72 Asset Management, L.P.0%SCHEDULE 13G/A
2026-05-15Orbimed Advisors LLC9.99%SCHEDULE 13G
2026-05-15BCLS II Equity Opportunities, LP9.99%SCHEDULE 13G/A
2026-08-14StemPoint Capital LP9.5%SCHEDULE 13G/A

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Where this comes from

Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.

Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.

Cite this page

Permanent URL: https://mentionfox.com/stakes/xilio-therapeutics
Last updated 2026-09-27
Primary record: SEC filing 1 · SEC filing 2 · SEC filing 3 · SEC filing 4
Xilio Therapeutics, Inc. 5%+ holders: 7 at 5% or more, largest Gilead Sciences, Inc. 19.9%. MentionFox, 2026-09-27. https://mentionfox.com/stakes/xilio-therapeutics