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5%+ stakes · Schedule 13D and 13G

Palisade Bio, Inc.: 5%+ holders

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Who has reported owning 5% or more of Palisade Bio, Inc., from Schedule 13D and 13G filings: each holder's stake as filed, the timeline, and the purpose each 13D states, quoted.

As of November 10, 2026, 9 holders' latest Schedule 13D or 13G filings report owning 5% or more of Palisade Bio, Inc. The largest reported stake is Janus Henderson Group Plc's, at 9.99%. 26 filings are on record since August 14, 2025 (Schedule 13G, December 8, 2025).

Octagon Capital Advisors LP also filed stake reports on 8 other companies ↓

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Key facts

  • · Reporting person: Soleus Capital Master Fund, L.P. · Sole voting: 0 · Shared voting: 14,996,154 · Sole dispositive: 0 · Shared dispositive: 14,996,154 · SCHEDULE 13G/A, 2026-11-09
  • · Reporting person: Vanguard Capital Management · Sole voting: 1,107,785 · Shared voting: 0 · Sole dispositive: 8,995,805 · Shared dispositive: 0 · SCHEDULE 13G, 2026-10-30
  • · Reporting person: Commodore Capital LP · Sole voting: 0 · Shared voting: 0 · Sole dispositive: 0 · Shared dispositive: 0 · SCHEDULE 13G/A, 2026-08-14
  • · Holder: Soleus Capital Master Fund, L.P. · Percent: 7.5% · SCHEDULE 13G/A
  • · Reporting person: BlackRock, Inc. · Sole voting: 10,326,107 · Shared voting: 0 · Sole dispositive: 10,436,760 · Shared dispositive: 0 · SCHEDULE 13G, 2026-07-29
At 5% or more9
Filings26
Latest filing2026-11-09

Palisade Bio, Inc. has 26 Schedule 13D or 13G filings on record since 2025-08-14. 9 holders' latest filing reports 5% or more of common stock, $0.01 par value per share. Each figure below is the holder's own, as filed, with the filing linked.

Holders

HolderPercentSharesLatestEvent date
Janus Henderson Group Plc9.99%14,885,421SCHEDULE 13G, 2025-12-082025-11-28
RA Capital Management, L.P.9.9%17,620,479SCHEDULE 13G/A, 2026-05-152026-03-31
Soleus Capital Master Fund, L.P.8.6%14,996,154SCHEDULE 13G/A, 2026-11-092026-09-30
Perceptive Advisors LLC7.9%14,113,863SCHEDULE 13G/A, 2026-05-152026-03-31
Octagon Capital Advisors LP6.4%9,567,898SCHEDULE 13G, 2026-02-102025-12-31
Franklin Resources, Inc.6%9,163,990SCHEDULE 13G, 2026-01-292025-12-31
BlackRock, Inc.6%10,436,760SCHEDULE 13G, 2026-07-292026-06-30
Ameriprise Financial, Inc.5.3%8,711,385SCHEDULE 13G, 2026-05-152026-03-31
Vanguard Capital Management5.16%8,995,805SCHEDULE 13G, 2026-10-302026-09-30
Armistice Capital, LLC4.99%478,945SCHEDULE 13G/A, 2025-08-142025-06-30
Squadron Master Fund LP3%4,500,000SCHEDULE 13G/A, 2026-02-172025-12-31
Point72 Asset Management, L.P.0.2%411,772SCHEDULE 13G/A, 2026-05-152026-03-31
Deep Track Capital, LP0%0SCHEDULE 13G/A, 2026-02-132025-12-31
Commodore Capital LP0%0SCHEDULE 13G/A, 2026-08-142026-06-30

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What the Full Report on Palisade Bio, Inc. covers

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Voting and dispositive power, as filed

Reporting personSole votingShared votingSole dispositiveShared dispositiveFiling
Soleus Capital Master Fund, L.P.014,996,154014,996,154SCHEDULE 13G/A, 2026-11-09
Soleus Capital, LLC014,996,154014,996,154SCHEDULE 13G/A, 2026-11-09
Soleus Capital Group, LLC014,996,154014,996,154SCHEDULE 13G/A, 2026-11-09
Soleus Capital Management, L.P.014,996,154014,996,154SCHEDULE 13G/A, 2026-11-09
Soleus GP, LLC014,996,154014,996,154SCHEDULE 13G/A, 2026-11-09
Guy Levy014,996,154014,996,154SCHEDULE 13G/A, 2026-11-09
BlackRock, Inc.10,326,107010,436,7600SCHEDULE 13G, 2026-07-29
Vanguard Capital Management1,107,78508,995,8050SCHEDULE 13G, 2026-10-30
Commodore Capital LP0000SCHEDULE 13G/A, 2026-08-14
Commodore Capital Master LP0000SCHEDULE 13G/A, 2026-08-14
Robert Egen Atkinson0000SCHEDULE 13G/A, 2026-08-14
Michael Kramarz0000SCHEDULE 13G/A, 2026-08-14

The latest filing identifies Palisade Bio, Inc. by CUSIP 696389402 and gives its principal executive office as 4600 South Syracuse Street, Suite 900, Denver, CO 80237 (SCHEDULE 13G/A, 2026-11-09).

Timeline

FiledHolderPercentFiling
2025-08-14Armistice Capital, LLC4.99%SCHEDULE 13G/A
2025-10-07Point72 Asset Management, L.P.6.2%SCHEDULE 13G
2025-10-08Deep Track Capital, LP9.99%SCHEDULE 13G
2025-10-08Commodore Capital LP9.9%SCHEDULE 13G
2025-10-08Squadron Capital Management LLC8.5%SCHEDULE 13G
2025-10-09Perceptive Advisors LLC9.99%SCHEDULE 13G
2025-10-09RA Capital Management, L.P.9.9%SCHEDULE 13G
2025-12-08Janus Henderson Group Plc9.99%SCHEDULE 13G
2026-01-29Franklin Resources, Inc.6%SCHEDULE 13G
2026-02-10Octagon Capital Advisors LP6.4%SCHEDULE 13G
2026-02-13Deep Track Capital, LP0%SCHEDULE 13G/A
2026-02-17Point72 Asset Management, L.P.7%SCHEDULE 13G/A
2026-02-17Perceptive Advisors LLC9.99%SCHEDULE 13G/A
2026-02-17RA Capital Management, L.P.9.9%SCHEDULE 13G/A
2026-02-17Squadron Master Fund LP3%SCHEDULE 13G/A
2026-05-15Point72 Asset Management, L.P.0.2%SCHEDULE 13G/A
2026-05-15Ameriprise Financial, Inc.5.3%SCHEDULE 13G
2026-05-15Perceptive Advisors LLC7.9%SCHEDULE 13G/A
2026-05-15RA Capital Management, L.P.9.9%SCHEDULE 13G/A
2026-05-15Commodore Capital LP7.2%SCHEDULE 13G/A
2026-05-27Soleus Capital Master Fund, L.P.5.4%SCHEDULE 13G
2026-07-29BlackRock, Inc.6%SCHEDULE 13G
2026-08-13Soleus Capital Master Fund, L.P.7.5%SCHEDULE 13G/A
2026-08-14Commodore Capital LP0%SCHEDULE 13G/A
2026-10-30Vanguard Capital Management5.16%SCHEDULE 13G
2026-11-09Soleus Capital Master Fund, L.P.8.6%SCHEDULE 13G/A

Questions about who owns Palisade Bio, Inc.

Who owns Palisade Bio, Inc.?

On this page, 9 holders' latest ownership filings report 5% or more of Palisade Bio, Inc.: Janus Henderson Group Plc (9.99%, Schedule 13G, filed 2025-12-08), RA Capital Management, L.P. (9.9%, Schedule 13G/A, filed 2026-05-15), Soleus Capital Master Fund, L.P. (8.6%, Schedule 13G/A, filed 2026-11-09), Perceptive Advisors LLC (7.9%, Schedule 13G/A, filed 2026-05-15) and Octagon Capital Advisors LP (6.4%, Schedule 13G, filed 2026-02-10); 4 more are listed above.

Who are the largest shareholders of Palisade Bio, Inc.?

By the share each holder's latest filing reports, the largest holders of Palisade Bio, Inc. on this page are Janus Henderson Group Plc (9.99%), RA Capital Management, L.P. (9.9%) and Soleus Capital Master Fund, L.P. (8.6%).

When did Janus Henderson Group Plc buy into Palisade Bio, Inc.?

The filings give report dates, not purchase dates. The earliest filing from Janus Henderson Group Plc on this page is the Schedule 13G, filed 2025-12-08, reporting 9.99%.

Is this an audit or a full list?

Neither. The ownership list on this page covers only Schedule 13D and 13G filings, which holders make once they own 5% or more of a class of shares (an amendment can report a stake that has since fallen below 5%); 26 such filings are shown here. It is not an audit and not a full cap table: holders who never reached 5% are not listed, and a stake can change after its latest filing.

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Where this comes from

Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.

Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.

Cite this page

Permanent URL: https://mentionfox.com/stakes/palisade-bio
Last updated 2026-11-10
Primary record: SEC filing 1 · SEC filing 2 · SEC filing 3 · SEC filing 4
Who owns 5% or more of Palisade Bio, Inc.? 9 holders at 5% or more, largest Janus Henderson Group Plc 9.99%. MentionFox, 2026-11-10. https://mentionfox.com/stakes/palisade-bio