As of November 6, 2026, one holder's latest Schedule 13D or 13G filing report owning 5% or more of NuCana plc. The largest reported stake is Hugh S. Griffith's, at 12%. One filing is on record since March 18, 2026 (Schedule 13D, March 18, 2026).
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NuCana plc has 1 Schedule 13D or 13G filing on record since 2026-03-18. 1 holder's latest filing reports 5% or more of ordinary shares, nominal value 0.0004 pounds sterling per share. Each figure below is the holder's own, as filed, with the filing linked.
Holders
| Holder | Percent | Shares | Latest | Event date |
|---|---|---|---|---|
| 12% | 2,829,961,890 | SCHEDULE 13D, 2026-03-18 | 2025-06-20 |
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Purpose of Transaction (Item 4)
Hugh S. Griffith
The Reporting Person acquired securities of the Issuer for investment purposes based on his belief that the Issuer's securities represented an attractive investment opportunity and in the ordinary course of his business of investing in securities for his own accounts. The Reporting Person has served as the Chief Executive Officer and as a director on the Issuer's Board of Directors since operations began in March 2008. In such capacity, the Reporting Person may have influence over the corporate activities of the Issuer, including activities which may relate to items described in paragraphs (a) through (j) of Item 4 of Schedule 13D. The Reporting Person does not have any current plans or proposals which relate to or would result in any transaction, event or action enumerated in paragraphs (a) through (j) of Item 4 of Schedule 13D. The Reporting Person may, at any time and from time to time, review or reconsider his position and/or change his purpose and/or formulate plans or proposals with respect thereto.Item 4 of the SCHEDULE 13D filed 2026-03-18
Timeline
| Filed | Holder | Percent | Filing |
|---|---|---|---|
| 2026-03-18 | Hugh S. Griffith | 12% | SCHEDULE 13D |
Also on the record for NuCana plc
| Date | Record | Figure | Our page | Source |
|---|---|---|---|---|
| May 7, 2025 | IPO filing, Form 424B4 | — | IPO filings | Source |
| May 2, 2025 | IPO filing, Form F-1/A | — | IPO filings | Source |
| April 29, 2025 | IPO filing, Form F-1/A | — | IPO filings | Source |
| April 24, 2025 | IPO filing, Form F-1 | — | IPO filings | Source |
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Where this comes from
Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.
Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.