Centessa Pharmaceuticals plc has 20 Schedule 13D or 13G filings on record since 2025-08-12. 2 holders' latest filing reports 5% or more of ordinary shares, nominal value 0.002 per share. Each figure below is the holder's own, as filed, with the filing linked.
Holders
| Holder | Percent | Shares | Latest | Event date |
|---|---|---|---|---|
| Avoro Capital Advisors LLC | 7.39% | 11,430,455 | SCHEDULE 13G/A, 2026-05-15 | 2026-03-31 |
| General Atlantic Cooperatief U.A. | 5% | 7,366,818 | SCHEDULE 13D/A, 2025-11-28 | 2025-11-25 |
| Adage Capital Management, L.P. | 0% | 0 | SCHEDULE 13G/A, 2026-08-12 | 2026-06-30 |
| Fmr LLC | 0% | 1,800 | SCHEDULE 13G/A, 2026-07-08 | 2026-06-30 |
| Pentwater Capital Management LP | 0% | 0 | SCHEDULE 13G/A, 2026-08-14 | 2026-06-30 |
| Farallon Capital Management, L.L.C. | 0% | 0 | SCHEDULE 13D/A, 2026-06-26 | 2026-06-24 |
| Medicxi Growth I LP | 0% | 0 | SCHEDULE 13G/A, 2026-08-04 | 2026-06-30 |
| Index Ventures Life Vi (Jersey) L.P. | 0% | 0 | SCHEDULE 13G/A, 2026-08-14 | 2026-06-30 |
Timeline
| Filed | Holder | Percent | Filing |
|---|---|---|---|
| 2025-08-12 | Adage Capital Management, L.P. | 6.29% | SCHEDULE 13G/A |
| 2025-11-05 | Fmr LLC | 7% | SCHEDULE 13G |
| 2025-11-13 | Adage Capital Management, L.P. | 7.48% | SCHEDULE 13G/A |
| 2025-11-14 | Avoro Capital Advisors LLC | 8.06% | SCHEDULE 13G |
| 2025-11-17 | General Atlantic Cooperatief U.A. | 6.6% | SCHEDULE 13D/A |
| 2025-11-28 | General Atlantic Cooperatief U.A. | 5% | SCHEDULE 13D/A |
| 2026-02-05 | Fmr LLC | 9.9% | SCHEDULE 13G/A |
| 2026-02-06 | Fmr LLC | 12.2% | SCHEDULE 13G/A |
| 2026-02-17 | Avoro Capital Advisors LLC | 9.97% | SCHEDULE 13G/A |
| 2026-05-06 | Fmr LLC | 7.5% | SCHEDULE 13G/A |
| 2026-05-13 | Adage Capital Management, L.P. | 5.77% | SCHEDULE 13G/A |
| 2026-05-15 | Avoro Capital Advisors LLC | 7.39% | SCHEDULE 13G/A |
| 2026-05-15 | Pentwater Capital Management LP | 5.3% | SCHEDULE 13G |
| 2026-06-24 | Farallon Capital Management, L.L.C. | 6.1% | SCHEDULE 13D |
| 2026-06-26 | Farallon Capital Management, L.L.C. | 0% | SCHEDULE 13D/A |
| 2026-07-08 | Fmr LLC | 0% | SCHEDULE 13G/A |
| 2026-08-04 | Medicxi Growth I LP | 0% | SCHEDULE 13G/A |
| 2026-08-12 | Adage Capital Management, L.P. | 0% | SCHEDULE 13G/A |
| 2026-08-14 | Pentwater Capital Management LP | 0% | SCHEDULE 13G/A |
| 2026-08-14 | Index Ventures Life Vi (Jersey) L.P. | 0% | SCHEDULE 13G/A |
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Where this comes from
Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.
Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.