About 40 employees are affected, according to LENZ Therapeutics, Inc.'s latest layoff filing, on October 28, 2026. As of November 4, 2026, LENZ Therapeutics, Inc. has reported this one exit or restructuring plan to the SEC on Form 8-K under Item 2.05. No WARN notice under its name is on file in the states covered here (Form 8-K, October 28, 2026).
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LENZ Therapeutics, Inc. reported 1 exit or restructuring plan on Form 8-K under Item 2.05, 1 of 1 stating how many employees or positions are affected. Each fact below is the filing's own sentence, quoted and linked. No WARN notice under this company's name is on file in the states covered here.
Did LENZ Therapeutics have layoffs in 2026? What its filings say
LENZ Therapeutics, Inc. (CIK 1815776) reported 1 exit or restructuring plan to the SEC on Form 8-K under Item 2.05. The sentences below are quoted from the filings as written.
Form 8-K filed 2026-10-28
Employees affected
On October 28, 2026, the board of directors of the Company (the "Board") approved a strategic reorganization to prioritize consumer marketing, allocate capital to maximize sales growth, and reduce operating expenses (the "Reorganization"), which included decreasing the Company's headcount by approximately 75% to approximately 40 full-time employees.
Expected charges
The Company estimates that it will incur non-recurring charges of approximately $5 million in connection with the Reorganization, primarily consisting of severance payments and related termination benefits.
Timing
The Company expects that substantially all of these charges will be incurred in the fourth quarter of 2026 and that the Reorganization will be substantially completed during the fourth quarter of 2026.
Also on the record for LENZ Therapeutics, Inc.
| Date | Record | Figure | Our page | Source |
|---|---|---|---|---|
| November 2, 2026 | Stake report, Schedule 13D/A, by RA Capital Management, L.P. | 0.2% of the class | 5%+ stakes | Source |
| October 28, 2026 | Leadership change: Daniel Chevallard appointed, President | — | Leadership changes | Source |
| October 27, 2026 | Stake report, Schedule 13G, by BlackRock Portfolio Management LLC | 5.2% of the class | 5%+ stakes | Source |
| October 21, 2026 | Stake report, Schedule 13G/A, by Millennium Management LLC | 3.7% of the class | 5%+ stakes | Source |
| September 8, 2026 | Stake report, Schedule 13G/A, by FMR LLC | 5.7% of the class | 5%+ stakes | Source |
| July 2, 2026 | Leadership change: Zach Scheiner departs | — | Leadership changes | Source |
| June 26, 2026 | Stake report, Schedule 13G, by Millennium Management LLC | 5.1% of the class | 5%+ stakes | Source |
| April 27, 2026 | Stake report, Schedule 13G, by BlackRock, Inc. | 5.8% of the class | 5%+ stakes | Source |
| April 8, 2026 | Stake report, Schedule 13G, by Squarepoint Ops LLC | 5.1% of the class | 5%+ stakes | Source |
| February 17, 2026 | Stake report, Schedule 13G/A, by Ridgeback Capital Investments L.P. | — | 5%+ stakes | Source |
| February 5, 2026 | Stake report, Schedule 13G/A, by FMR LLC | 11.8% of the class | 5%+ stakes | Source |
| January 21, 2026 | Stake report, Schedule 13G/A, by BlackRock, Inc. | 4.9% of the class | 5%+ stakes | Source |
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More on LENZ Therapeutics, Inc. and the records around it.
LENZ Therapeutics, Inc. elsewhere on the record
- 5%+ stake filings Nov 2026
- Leadership changes Jul 2026
- Who owns it
Companies that share a holder
- Squarepoint Ops LLC also filed stake reports on 1 other company: Cartesian Therapeutics, Inc. (Mar 2026)
- Ridgeback Capital Investments L.P. also filed stake reports on 3 other companies: Replimune Group, Inc. (Aug 2026), iTeos Therapeutics, Inc. (Nov 2025), Semler Scientific, Inc. (Nov 2025)
- Versant Venture Capital VI, L.P. also filed stake reports on 3 other companies: Tempest Therapeutics, Inc. (Apr 2026), Monte Rosa Therapeutics, Inc. (Jan 2026), LAVA Therapeutics N.V. (Sep 2025)
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Public companies must also report to the SEC, on Form 8-K under Item 2.05, when they commit to an exit or restructuring plan that will cost them material charges, which is how most large layoffs and closures by listed companies are disclosed. Those filings are national, so they cover companies in every state. Each sentence shown from one is quoted exactly and linked to the filing; where a filing does not state a figure, none is shown.
Where this comes from
Employers covered by the federal WARN Act, and by the stricter laws some states add, must give written notice before a mass layoff or a site closure. The state labor department publishes those notices. Every row here is one of them, taken from that state's own published file and linked to it, so each figure can be checked at the source.
A notice states the employer, the location, the number of employees affected, and when the layoff or closure takes effect. It does not state a reason, and neither does this page. Where a company also appears in SEC filings under the same name and in the same state, its recorded fundraising is shown alongside, as a matter of record rather than as an explanation. New Jersey and Pennsylvania list a notice under the month it was posted or received, not the day, so their notices show a month. Tennessee gives the county rather than the city.
Who owns LENZ Therapeutics, Inc.? Owners, funding and legal record
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