Fractyl Health, Inc.'s latest layoff filing, on October 22, 2026, states a cut of about 45% of its workforce. As of October 27, 2026, it has reported this one exit or restructuring plan to the SEC on Form 8-K under Item 2.05. No WARN notice under its name is on file in the states covered here (Form 8-K, October 22, 2026).
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Fractyl Health, Inc. reported 1 exit or restructuring plan on Form 8-K under Item 2.05. Each fact below is the filing's own sentence, quoted and linked. No WARN notice under this company's name is on file in the states covered here.
Did Fractyl Health have layoffs in 2026? What its filings say
Fractyl Health, Inc. (CIK 1572616) reported 1 exit or restructuring plan to the SEC on Form 8-K under Item 2.05. The sentences below are quoted from the filings as written.
Form 8-K filed 2026-10-22
Share of workforce
As part of the plan, the Company will reduce its workforce by approximately 45% of the Company's current headcount.
Expected charges
The Company estimates that it will incur charges of approximately $2 million for severance and other employee termination-related costs, with the majority of such costs to be incurred in the fourth quarter of 2026.
Timing
The reduction in force is expected to be completed during the fourth quarter of 2026.
Also on the record for Fractyl Health, Inc.
| Date | Record | Figure | Our page | Source |
|---|---|---|---|---|
| October 22, 2026 | Leadership change: Harith Rajagopalan appointed, Chief Executive Officer | — | Leadership changes | Source |
| October 13, 2026 | Stake report, Schedule 13G, by Catalio Capital Management, LP | 5.6% of the class | 5%+ stakes | Source |
| May 15, 2026 | Stake report, Schedule 13G/A, by 683 Capital Management, LLC | 4.81% of the class | 5%+ stakes | Source |
| May 15, 2026 | Stake report, Schedule 13G/A, by Nantahala Capital Management, LLC | 9.99% of the class | 5%+ stakes | Source |
| May 13, 2026 | Stake report, Schedule 13G/A, by SilverArc Capital Management, LLC | 2.3% of the class | 5%+ stakes | Source |
| February 17, 2026 | Stake report, Schedule 13G/A, by Alyeska Investment Group, L.P. | 4.97% of the class | 5%+ stakes | Source |
| February 12, 2026 | Stake report, Schedule 13G/A, by Ajay Royan | 4.7% of the class | 5%+ stakes | Source |
| February 4, 2026 | Stake report, Schedule 13G/A, by CVF, LLC | 3.4% of the class | 5%+ stakes | Source |
| November 14, 2025 | Stake report, Schedule 13G, by Alyeska Investment Group, L.P. | 9.7% of the class | 5%+ stakes | Source |
| November 14, 2025 | Stake report, Schedule 13G, by Nantahala Capital Management, LLC | 9.99% of the class | 5%+ stakes | Source |
| November 14, 2025 | Stake report, Schedule 13G, by SilverArc Capital Management, LLC | 8.02% of the class | 5%+ stakes | Source |
| November 14, 2025 | Stake report, Schedule 13G/A, by Maverick Capital, Ltd. | 3.1% of the class | 5%+ stakes | Source |
Keep reading
More on Fractyl Health, Inc. and the records around it.
Fractyl Health, Inc. elsewhere on the record
- 5%+ stake filings Oct 2026
- Who owns it
Companies that share a holder
- Mithril LP also filed stake reports on 1 other company: BlackSky Technology, Inc. (Aug 2026)
- Maverick Capital, Ltd. also filed stake reports on 5 other companies: Infleqtion, Inc. (May 2026), Invivyd, Inc. (Feb 2026), Peabody Energy Corporation (Feb 2026)
- SilverArc Capital Management, LLC also filed stake reports on 8 other companies: Cellectar Biosciences Inc (Aug 2026), ELUTIA INC. (Aug 2026), TELA BIO, INC. (Aug 2026)
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Public companies must also report to the SEC, on Form 8-K under Item 2.05, when they commit to an exit or restructuring plan that will cost them material charges, which is how most large layoffs and closures by listed companies are disclosed. Those filings are national, so they cover companies in every state. Each sentence shown from one is quoted exactly and linked to the filing; where a filing does not state a figure, none is shown.
Where this comes from
Employers covered by the federal WARN Act, and by the stricter laws some states add, must give written notice before a mass layoff or a site closure. The state labor department publishes those notices. Every row here is one of them, taken from that state's own published file and linked to it, so each figure can be checked at the source.
A notice states the employer, the location, the number of employees affected, and when the layoff or closure takes effect. It does not state a reason, and neither does this page. Where a company also appears in SEC filings under the same name and in the same state, its recorded fundraising is shown alongside, as a matter of record rather than as an explanation. New Jersey and Pennsylvania list a notice under the month it was posted or received, not the day, so their notices show a month. Tennessee gives the county rather than the city.
Who owns Fractyl Health, Inc.? Owners, funding and legal record
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