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item (YC F25) — The AI-Native CRM that works for you

item connects to all your customer tools, gathers and enriches context automatically, and becomes your company’s source of truth — one place where your team and your AI agents share the full picture to act autonomously. At the center is the Assistant — your sidekick for daily work.

item is a Y Combinator company in the Fall 2025 batch. Its directory entry describes it as: The AI-Native CRM that works for you. The founders listed are Andres Santanilla (Founder/CEO), Akshay Guthal (Founder/CTO) (Y Combinator directory entry, November 3, 2025).

6 more companies from YC Fall 2025 ↓

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item

New accelerator entry · 2025-11-03 · the record

Fall 2025
batch
6
people
Early
stage
United States of America
region
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What the record says

BatchFall 2025
Announced2025-11-03
StageEarly
StatusActive
Team size6
IndustryB2B
Sub-industryB2B -> Sales
SectorsB2B, CRM, Automation, AI Assistant
RegionsUnited States of America, America / Canada
BasedSan Francisco, CA, USA
HiringYes
Sitehttps://item.app
Founded2024
YC group partnerPete Koomen

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Also in YC Fall 2025

Same batch, B2B first.

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In their words

item connects to all your customer tools, gathers and enriches context automatically, and becomes your company’s source of truth — one place where your team and your AI agents share the full picture to act autonomously. At the center is the Assistant — your sidekick for daily work. It can send follow-ups, research leads, or add deals with a simple prompt. No complex UI, drop-downs or fields, simply ask. For repeatable work, you build Agents that you can train like new hires, simply by writing documents that describe your processes. item Agents run business processes across sales, support, and account management autonomously.

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What the Full Report on item covers

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  2. Which Company This Is

  3. What They Do, And How The Money Works

  4. Who Runs It, And How To Reach Them

  5. The Money: Funding, Valuation, Runway

  6. Who Pays Them, And Who They Are Up Against

  7. Warning Bells

  8. Sources

    1 cited source found

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item: Accepted into Y Combinator Fall 2025
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Permanent URL: https://mentionfox.com/funding/yc-item
Last updated 2026-10-27
Primary record: Y Combinator directory entry
item (YC F25) — The AI-Native CRM that works for you. MentionFox, 2026-10-27. https://mentionfox.com/funding/yc-item