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Cofactor Genomics (YC S15) — Cofactor closes the precision medicine gap with predictive diagnostics

Cofactor uses RNA and Predictive Immune Modeling to build better biomarkers and improve patient outcomes. Led by Jarret Glasscock and a group of expert human genome scientists,Cofactor has built a new category of diagnostic technology powered by unique and powerful RNA data models built on terabytes of data.

Cofactor Genomics is a Y Combinator company in the Summer 2015 batch. Its directory entry describes it as: Cofactor closes the precision medicine gap with predictive diagnostics. The founders listed are Dave Messina (Founder/COO), Jarret Glasscock (Founder/CTO) (Y Combinator directory entry, June 4, 2015).

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Cofactor Genomics

New accelerator entry · 2015-06-04 · the record

Summer 2015
batch
13
people
Growth
stage
United States of America
region
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What the record says

BatchSummer 2015
Announced2015-06-04
StageGrowth
StatusActive
Team size13
IndustryHealthcare
Sub-industryHealthcare -> Diagnostics
SectorsMedical Devices, Biotech, Diagnostics
RegionsUnited States of America, America / Canada, Remote, Partly Remote
BasedSt. Louis, MO, USA
HiringNo
Sitehttp://cofactorgenomics.com

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Also in YC Summer 2015

Same batch, Healthcare first.

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In their words

Cofactor uses RNA and Predictive Immune Modeling to build better biomarkers and improve patient outcomes. Led by Jarret Glasscock and a group of expert human genome scientists,Cofactor has built a new category of diagnostic technology powered by unique and powerful RNA data models built on terabytes of data. The team recently had their technology validation peer-reviewed by the organizations that set standards for diagnostic technology (CAP, AMP) and is publishing in the Journal of Molecular Diagnostics. In addition, the team made news when Cancer Physicians who sit on the committee for patient treatment guidelines (NCCN) presented a clinical study using Cofactor’s technology showing superiority in predicting the patients who will respond to immunotherapy. This initial application is an acute problem recognized widely in the rapidly developing immunotherapy industry and represents north of a billion dollar TAM. After a number of recent key milestones, the team is taking the technology more broadly to 50% of cancers diagnosed in the US. Current investors include Menlo Ventures, DCVC, and Ascension Ventures (this last investor representing the funding arm for 13 National U.S. Healthcare Systems).

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Cofactor Genomics: Accepted into Y Combinator Summer 2015
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Permanent URL: https://mentionfox.com/funding/yc-cofactor-genomics
Last updated 2026-10-20
Primary record: Y Combinator directory entry
Cofactor Genomics (YC S15) — Cofactor closes the precision medicine gap with predictive diagnostics. MentionFox, 2026-10-20. https://mentionfox.com/funding/yc-cofactor-genomics