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5%+ stakes · Schedule 13D and 13G

Denali Therapeutics Inc.: 5%+ holders

Who has reported owning 5% or more of Denali Therapeutics Inc., from Schedule 13D and 13G filings: each holder's stake as filed, the timeline, and the purpose each 13D states, quoted.

At 5% or more2
Filings7
Latest filing2026-08-04

Denali Therapeutics Inc. has 7 Schedule 13D or 13G filings on record since 2025-08-12. 2 holders' latest filing reports 5% or more of common stock. Each figure below is the holder's own, as filed, with the filing linked.

Holders

HolderPercentSharesLatestEvent date
T. Rowe Price Investment Management, Inc.10.2%16,178,963SCHEDULE 13G/A, 2026-07-082026-06-30
Baillie Gifford & Co7.5%11,960,230SCHEDULE 13G/A, 2026-08-042026-06-30
Fmr LLC4.2%6,672,999SCHEDULE 13G/A, 2026-05-062026-03-31
Wellington Management Group LLP3.9%5,664,733SCHEDULE 13G/A, 2025-08-122025-06-30
The Vanguard Group0%0SCHEDULE 13G/A, 2026-03-262026-03-13

Timeline

FiledHolderPercentFiling
2025-08-12Wellington Management Group LLP3.9%SCHEDULE 13G/A
2025-11-05Fmr LLC5.8%SCHEDULE 13G/A
2026-03-26The Vanguard Group0%SCHEDULE 13G/A
2026-05-06Fmr LLC4.2%SCHEDULE 13G/A
2026-05-15T. Rowe Price Investment Management, Inc.5.4%SCHEDULE 13G
2026-07-08T. Rowe Price Investment Management, Inc.10.2%SCHEDULE 13G/A
2026-08-04Baillie Gifford & Co7.5%SCHEDULE 13G/A

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Where this comes from

Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.

Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.

Cite this page

Permanent URL: https://mentionfox.com/stakes/denali-therapeutics
Last updated 2026-09-27
Primary record: SEC filing 1 · SEC filing 2 · SEC filing 3 · SEC filing 4
Denali Therapeutics Inc. 5%+ holders: 2 at 5% or more, largest T. Rowe Price Investment Management, Inc. 10.2%. MentionFox, 2026-09-27. https://mentionfox.com/stakes/denali-therapeutics