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5%+ stakes · Schedule 13D and 13G

Rhythm Pharmaceuticals, Inc.: 5%+ holders

Who has reported owning 5% or more of Rhythm Pharmaceuticals, Inc., from Schedule 13D and 13G filings: each holder's stake as filed, the timeline, and the purpose each 13D states, quoted.

At 5% or more4
Filings10
Latest filing2026-05-15

Rhythm Pharmaceuticals, Inc. has 10 Schedule 13D or 13G filings on record since 2025-08-14. 4 holders' latest filing reports 5% or more of common stock, $0.001 par value per share. Each figure below is the holder's own, as filed, with the filing linked.

Holders

HolderPercentSharesLatestEvent date
RA Capital Management, L.P.9.9%6,666,837SCHEDULE 13G/A, 2026-02-172025-12-31
Primecap Management Co5.21%3,478,669SCHEDULE 13G/A, 2026-02-122025-12-31
Perceptive Advisors LLC5.1%3,519,626SCHEDULE 13G/A, 2026-05-152026-03-31
Vanguard Capital Management5.02%3,432,949SCHEDULE 13G, 2026-04-302026-03-31
The Vanguard Group0%0SCHEDULE 13G/A, 2026-03-272026-03-13

Timeline

FiledHolderPercentFiling
2025-08-14Primecap Management Co7.67%SCHEDULE 13G/A
2025-08-14RA Capital Management, L.P.8.7%SCHEDULE 13G/A
2025-10-30The Vanguard Group7.52%SCHEDULE 13G/A
2025-11-14Primecap Management Co6.42%SCHEDULE 13G/A
2026-01-30The Vanguard Group9.3%SCHEDULE 13G/A
2026-02-12Primecap Management Co5.21%SCHEDULE 13G/A
2026-02-17RA Capital Management, L.P.9.9%SCHEDULE 13G/A
2026-03-27The Vanguard Group0%SCHEDULE 13G/A
2026-04-30Vanguard Capital Management5.02%SCHEDULE 13G
2026-05-15Perceptive Advisors LLC5.1%SCHEDULE 13G/A

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Where this comes from

Anyone who comes to own more than 5% of a class of a listed company's voting shares has to tell the SEC. A holder who may seek to change or influence the company files Schedule 13D, and has to say in Item 4, "Purpose of Transaction", what it intends to do. A holder with no such intent, such as many index and passive funds, may file the shorter Schedule 13G. Both are amended when the stake changes, including when it falls below 5%.

Every row here is one of those filings, linked to the filing itself. Percentages and share counts are exactly as the holder filed them, for the holder the filing names; an amendment showing a lower figure is shown as filed. Item 4 text is quoted word for word. Where a 13D's Item 4 contains a sentence stating a definite intent to influence the company, that sentence is marked and quoted; the page does not describe the holder or its motives beyond the words it filed. Nothing here is investment advice.

Cite this page

Permanent URL: https://mentionfox.com/stakes/rhythm-pharmaceuticals
Last updated 2026-09-27
Primary record: SEC filing 1 · SEC filing 2 · SEC filing 3 · SEC filing 4
Rhythm Pharmaceuticals, Inc. 5%+ holders: 4 at 5% or more, largest RA Capital Management, L.P. 9.9%. MentionFox, 2026-09-27. https://mentionfox.com/stakes/rhythm-pharmaceuticals